Protective role of propolis against reproductive toxicity of triphenyltin in male rabbits

Triphenyltin (TPT) is known to cause endocrine disruption, reproductive toxicity and a decrease in testosterone production. It is involved in the production of reactive oxygen species. Propolis has been reported to be an important antioxidant. Therefore, the present study aimed to elucidate the poss...

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Veröffentlicht in:	Food and chemical toxicology 2010-07, Vol.48 (7), p.1846-1852
Hauptverfasser:	Yousef, Mokhtar I., Kamel, Kamel I., Hassan, Mervat S., El-Morsy, Ahmed M.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antioxidants Antioxidants - metabolism Biological and medical sciences body weight Body Weight - drug effects Chemical and industrial products toxicology. Toxic occupational diseases Eating - drug effects enzyme activity epididymis Epididymis - drug effects Free radicals glutathione transferase Infertility, Male - chemically induced Infertility, Male - prevention & control lactate dehydrogenase lipid peroxidation Male Medical sciences Metals and various inorganic compounds oral administration Organ Size - drug effects Organotin Compounds - antagonists & inhibitors Organotin Compounds - toxicity Propolis Propolis - pharmacology protective effect Rabbits Reaction Time - drug effects reactive oxygen species reproductive performance Reproductive toxicity reproductive toxicology Semen - cytology Semen - drug effects Semen - enzymology seminal plasma Seminal plasma biochemical parameters Sperm Count testes Testicular Diseases - chemically induced Testicular Diseases - physiopathology Testicular Diseases - prevention & control Testis - drug effects testosterone Testosterone - blood thiobarbituric acid-reactive substances toxicity Toxicology transaminases Triphenyltin chloride
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