Solution oligomerization of the rev protein of HIV-1: Implications for function

rev is an RNA-binding protein of human immunodeficiency virus-1 and is required for the expression of incompletely spliced viral transcripts. Oligomerization of rev is thought to be associated with RNA binding and rev function. Here, we have characterized the oligomerization of rev using equilibrium...

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Veröffentlicht in:	Biochemistry (Easton) 1993-11, Vol.32 (44), p.11769-11775
Hauptverfasser:	Cole, James L, Gehman, John D, Shafer, Jules A, Kuo, Lawrence C
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Biological and medical sciences Cloning, Molecular Escherichia coli Fundamental and applied biological sciences. Psychology Gene Products, rev - chemistry Gene Products, rev - isolation & purification Gene Products, rev - metabolism HIV-1 - metabolism human immunodeficiency virus 1 Hydrogen-Ion Concentration In solution. Condensed state. Thin layers Kinetics Macromolecular Substances Mathematics Molecular biophysics Physico-chemical properties of biomolecules Recombinant Proteins - chemistry Recombinant Proteins - isolation & purification Recombinant Proteins - metabolism rev Gene Products, Human Immunodeficiency Virus RNA, Viral - isolation & purification RNA, Viral - metabolism Solutions Thermodynamics
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