Alternative splicing of the p53 tumor suppressor gene in the Molt-4 T-lymphoblastic leukemia cell line

The expression of the p53 tumor suppressor gene in ten human cell lines (nine cancers and one normal) was studied using reverse transcription, polymerase chain reaction (PCR) and direct sequencing. Using P53U and P53D primers for amplifying a 371-base pair (bp) target fragment spanning exons 7–10 of...

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Veröffentlicht in:	Cancer letters 1993-09, Vol.73 (2), p.141-148
Hauptverfasser:	Chow, Vincent T.K., Quek, H.H., Tock, Edward P.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative splicing Alternative Splicing - genetics Amino Acid Sequence Base Sequence Biological and medical sciences Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes DNA, Neoplasm - genetics Fundamental and applied biological sciences. Psychology Gene Expression - genetics Genes, p53 - genetics Humans Leukemia-Lymphoma, Adult T-Cell - genetics Molecular and cellular biology Molecular Sequence Data Molt-4 cell line p53 gene Polymerase Chain Reaction Sequence Analysis, DNA Transcription, Genetic - genetics Tumor Cells, Cultured
Online-Zugang:	Volltext
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