Artificial siderophores. 1. Synthesis and microbial iron transport capabilities

Several di- and trihydroxamate analogues of natural microbial iron chelators have been prepared. The syntheses involved linkage of core structural units, including pyridinedicarboxylic acid, benzenetricarboxylic acid, nitrilotriacetic acid, and tricarballylic acid, by amide bonds to 1-amino-omega-(h...

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Veröffentlicht in:	Journal of medicinal chemistry 1985-03, Vol.28 (3), p.317-323
Hauptverfasser:	Lee, Byung Hyun, Miller, Marvin J, Prody, Catherine A, Neilands, John B
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Transport - drug effects Escherichia coli - metabolism Iron - metabolism Iron Chelating Agents - chemical synthesis Iron Chelating Agents - pharmacology Siderophores
Online-Zugang:	Volltext
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