Developmental differences in acute nigrostriatal and mesocorticolimbic system response to haloperidol

Dose-dependent effects of haloperidol (2.66 nmol/kg to 79.8 mmol/kg, IP) on levels of dopamine, homovanillic acid (HVA) and dihydroxyphenylacetic acid (DOPAC) were assessed in the corpus striatum, nucleus accumbens, and medial prefrontal cortex (PFCTX) of 18-, 30-, and 110-day-old rats. Eighteen-day...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 1993-09, Vol.9 (2), p.147-156
Hauptverfasser:	TEICHER, M. H, BARBER, N. I, GELBARD, H. A, GALLITANO, A. L, CAMPBELL, A, MARSH, E, BALDESSARINI, R. J
Format:	Artikel
Sprache:	eng
Schlagworte:	3,4-Dihydroxyphenylacetic Acid - metabolism Aging - metabolism Animals Biological and medical sciences Corpus Striatum - drug effects Corpus Striatum - growth & development Corpus Striatum - metabolism Dopamine - physiology Dose-Response Relationship, Drug Female Haloperidol - pharmacology Homovanillic Acid - metabolism Limbic System - drug effects Limbic System - growth & development Limbic System - metabolism Male Medical sciences Neuropharmacology Pharmacology. Drug treatments Prefrontal Cortex - drug effects Prefrontal Cortex - growth & development Prefrontal Cortex - metabolism Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Rats Rats, Sprague-Dawley Substantia Nigra - drug effects Substantia Nigra - growth & development Substantia Nigra - metabolism
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