Tuberculous Spondylitis and Intermittent Chemotherapy in Childhood
The general characteristics and treatment of childhood tuberculous spondylitis are reviewed. Most of the patients (79 per cent) were under 5 years old with girls being in greater number. Twenty-six patients used classical antituberculous chemotherapy and five were given intermittent chemotherapy. Th...
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| Veröffentlicht in: | Journal of tropical pediatrics (1980) 1993-08, Vol.39 (4), p.255-257 |
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| container_title | Journal of tropical pediatrics (1980) |
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| creator | Toppare, M. F. Göcmen, A. Kiper, N. Gögüs, T. |
| description | The general characteristics and treatment of childhood tuberculous spondylitis are reviewed. Most of the patients (79 per cent) were under 5 years old with girls being in greater number. Twenty-six patients used classical antituberculous chemotherapy and five were given intermittent chemotherapy. There was no significant difference in the mean period of inactivation of the disease (2.8 v. 2.9 months) or in posttreatment angle of kyphosis (33° v. 37.6°) between the classical and intermittent chemotherapy groups. In addition to drug therapy, plaster jacket and immobilization were adequate in four children whereas 27 underwent surgery with only two requiring radical operations. In children with tuberculous spondylitis, intermittent drug treatment is a good alternative due to effectiveness and convenience of use and radical surgery should be reserved for selected cases. |
| doi_str_mv | 10.1093/tropej/39.4.255 |
| format | Article |
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In children with tuberculous spondylitis, intermittent drug treatment is a good alternative due to effectiveness and convenience of use and radical surgery should be reserved for selected cases.</description><identifier>ISSN: 0142-6338</identifier><identifier>EISSN: 1465-3664</identifier><identifier>DOI: 10.1093/tropej/39.4.255</identifier><identifier>PMID: 8411322</identifier><identifier>CODEN: JTRPAO</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Bacterial arthritis and osteitis ; Bacterial diseases ; Biological and medical sciences ; Child, Preschool ; Drug Therapy, Combination ; Female ; Human bacterial diseases ; Humans ; Infectious diseases ; Isoniazid - therapeutic use ; Lumbar Vertebrae - physiopathology ; Male ; Medical sciences ; Psoas Abscess - physiopathology ; Spondylitis - diagnosis ; Spondylitis - drug therapy ; Spondylitis - physiopathology ; Streptomycin - administration & dosage ; Streptomycin - therapeutic use ; Thoracic Vertebrae - physiopathology ; Tropical medicine</subject><ispartof>Journal of tropical pediatrics (1980), 1993-08, Vol.39 (4), p.255-257</ispartof><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c359t-904a93312dad0a97ee75e0a6d0065e23faeaddd27312f4f9cd74df2575eb5a213</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4855088$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8411322$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Toppare, M. F.</creatorcontrib><creatorcontrib>Göcmen, A.</creatorcontrib><creatorcontrib>Kiper, N.</creatorcontrib><creatorcontrib>Gögüs, T.</creatorcontrib><title>Tuberculous Spondylitis and Intermittent Chemotherapy in Childhood</title><title>Journal of tropical pediatrics (1980)</title><addtitle>J Trop Pediatr</addtitle><description>The general characteristics and treatment of childhood tuberculous spondylitis are reviewed. Most of the patients (79 per cent) were under 5 years old with girls being in greater number. Twenty-six patients used classical antituberculous chemotherapy and five were given intermittent chemotherapy. There was no significant difference in the mean period of inactivation of the disease (2.8 v. 2.9 months) or in posttreatment angle of kyphosis (33° v. 37.6°) between the classical and intermittent chemotherapy groups. In addition to drug therapy, plaster jacket and immobilization were adequate in four children whereas 27 underwent surgery with only two requiring radical operations. In children with tuberculous spondylitis, intermittent drug treatment is a good alternative due to effectiveness and convenience of use and radical surgery should be reserved for selected cases.</description><subject>Bacterial arthritis and osteitis</subject><subject>Bacterial diseases</subject><subject>Biological and medical sciences</subject><subject>Child, Preschool</subject><subject>Drug Therapy, Combination</subject><subject>Female</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Isoniazid - therapeutic use</subject><subject>Lumbar Vertebrae - physiopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Psoas Abscess - physiopathology</subject><subject>Spondylitis - diagnosis</subject><subject>Spondylitis - drug therapy</subject><subject>Spondylitis - physiopathology</subject><subject>Streptomycin - administration & dosage</subject><subject>Streptomycin - therapeutic use</subject><subject>Thoracic Vertebrae - physiopathology</subject><subject>Tropical medicine</subject><issn>0142-6338</issn><issn>1465-3664</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtLAzEURoMoWh9rV8IsxN20ec_MUovaFkXQCuImpJM7NDovkwzYf2-kpavL5Tv343IQuiR4THDBJsF1PXxNWDHmYyrEARoRLkXKpOSHaIQJp6lkLD9Bp95_YYxpzvkxOs45IYzSEbpbDitw5VB3g0_e-q41m9oG6xPdmmTeBnCNDQHakEzX0HRhDU73m8S2cbe1WXedOUdHla49XOzmGXp_uF9OZ-nTy-N8evuUlkwUIS0w1wVjhBptsC4ygEwA1tJgLAVQVmnQxhiaRaTiVVGajJuKikithKaEnaGbbW_vup8BfFCN9SXUtW4hfq8yibEgVEZwsgVL13nvoFK9s412G0Ww-remttYUKxRX0Vq8uNpVD6sGzJ7faYr59S7XvtR15XRbWr_HeC4EzvOIpVvM-gC_-1i7byUzlgk1-_hUi9nrYrZYPquM_QFLp4an</recordid><startdate>19930801</startdate><enddate>19930801</enddate><creator>Toppare, M. F.</creator><creator>Göcmen, A.</creator><creator>Kiper, N.</creator><creator>Gögüs, T.</creator><general>Oxford University Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19930801</creationdate><title>Tuberculous Spondylitis and Intermittent Chemotherapy in Childhood</title><author>Toppare, M. 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F.</creatorcontrib><creatorcontrib>Göcmen, A.</creatorcontrib><creatorcontrib>Kiper, N.</creatorcontrib><creatorcontrib>Gögüs, T.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of tropical pediatrics (1980)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Toppare, M. F.</au><au>Göcmen, A.</au><au>Kiper, N.</au><au>Gögüs, T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tuberculous Spondylitis and Intermittent Chemotherapy in Childhood</atitle><jtitle>Journal of tropical pediatrics (1980)</jtitle><addtitle>J Trop Pediatr</addtitle><date>1993-08-01</date><risdate>1993</risdate><volume>39</volume><issue>4</issue><spage>255</spage><epage>257</epage><pages>255-257</pages><issn>0142-6338</issn><eissn>1465-3664</eissn><coden>JTRPAO</coden><abstract>The general characteristics and treatment of childhood tuberculous spondylitis are reviewed. Most of the patients (79 per cent) were under 5 years old with girls being in greater number. Twenty-six patients used classical antituberculous chemotherapy and five were given intermittent chemotherapy. There was no significant difference in the mean period of inactivation of the disease (2.8 v. 2.9 months) or in posttreatment angle of kyphosis (33° v. 37.6°) between the classical and intermittent chemotherapy groups. In addition to drug therapy, plaster jacket and immobilization were adequate in four children whereas 27 underwent surgery with only two requiring radical operations. In children with tuberculous spondylitis, intermittent drug treatment is a good alternative due to effectiveness and convenience of use and radical surgery should be reserved for selected cases.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>8411322</pmid><doi>10.1093/tropej/39.4.255</doi><tpages>3</tpages></addata></record> |
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| issn | 0142-6338 1465-3664 |
| language | eng |
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| source | MEDLINE; Oxford University Press Journals Digital Archive Legacy |
| subjects | Bacterial arthritis and osteitis Bacterial diseases Biological and medical sciences Child, Preschool Drug Therapy, Combination Female Human bacterial diseases Humans Infectious diseases Isoniazid - therapeutic use Lumbar Vertebrae - physiopathology Male Medical sciences Psoas Abscess - physiopathology Spondylitis - diagnosis Spondylitis - drug therapy Spondylitis - physiopathology Streptomycin - administration & dosage Streptomycin - therapeutic use Thoracic Vertebrae - physiopathology Tropical medicine |
| title | Tuberculous Spondylitis and Intermittent Chemotherapy in Childhood |
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