β-adrenergic stimulation does not regulate Na pump function in voltage-clamped ventricular myocytes of the rat heart

Na pump current was measured in rat ventricular myocytes to determine if beta-adrenergic stimulation can directly modulate Na,K-ATPase activity. Enzymatically-isolated heart cells were voltage-clamped with a single patch electrode and Na pump current was briefly activated by rapidly increasing extra...

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Veröffentlicht in:	Pflügers Archiv 1993-08, Vol.424 (3-4), p.361-363
Hauptverfasser:	ISHIZUKA, N, BERLIN, J. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Agonists - pharmacology Animals Barium - metabolism Biological and medical sciences Dialysis Electrodes Electrophysiology Fundamental and applied biological sciences. Psychology Heart Heart - drug effects In Vitro Techniques Isoproterenol - pharmacology Myocardium - cytology Myocardium - enzymology Potassium - metabolism Rats Sodium-Potassium-Exchanging ATPase - metabolism Vertebrates: cardiovascular system
Online-Zugang:	Volltext
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