Hepatitis B Mass Immunization of Adolescents: A Pilot Study in a Community

The National Type Specific Hepatitis Surveillance System (SEIEVA) and seroepidemiological studies have shown that in addition to newborns from mothers who are carriers for hepatitis B surface antigen (HBsAg), adolescents are at high risk of acquiring type B hepatitis virus because of increasing impo...

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Veröffentlicht in:European journal of epidemiology 1993-05, Vol.9 (3), p.307-310
Hauptverfasser: Plaitano, S., Sagliocca, L., Mele, A., Bove, C., Protano, D., Adamo, B., Palumbo, F., Cauletti, M., Franco, E., Pasquini, P.
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container_end_page 310
container_issue 3
container_start_page 307
container_title European journal of epidemiology
container_volume 9
creator Plaitano, S.
Sagliocca, L.
Mele, A.
Bove, C.
Protano, D.
Adamo, B.
Palumbo, F.
Cauletti, M.
Franco, E.
Pasquini, P.
description The National Type Specific Hepatitis Surveillance System (SEIEVA) and seroepidemiological studies have shown that in addition to newborns from mothers who are carriers for hepatitis B surface antigen (HBsAg), adolescents are at high risk of acquiring type B hepatitis virus because of increasing importance of the heterosexual transmission of this virus. In order to evaluate logistic problems and acceptance rate of adolescents to mass vaccination against hepatitis B, a pilot study was carried out among all 7th grade children registered in the 9 schools of an hepatitis B endemic area located in the suburbs of Naples. After meetings held by the local health department with school teachers and parents, 1219 out of 1250 (97.5%) invited children received the first dose of hepatitis B vaccine; 1215 and 1209 received, respectively, the second and third doses. Anti-hepatitis B surface antigen (anti-HBs) values were studied in 406 subjects one month after the third dose, and 21 out of 406 (5.2%) had anti-HBs values less than 10 IU/L. We consider 95% of subjects with anti-HBs values greater than 9 IU/L a good achievement for a field vaccination program. The high acceptance rate of vaccination found in our study outlines the importance of active offer of vaccination combined with school involvement.
doi_str_mv 10.1007/BF00146268
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In order to evaluate logistic problems and acceptance rate of adolescents to mass vaccination against hepatitis B, a pilot study was carried out among all 7th grade children registered in the 9 schools of an hepatitis B endemic area located in the suburbs of Naples. After meetings held by the local health department with school teachers and parents, 1219 out of 1250 (97.5%) invited children received the first dose of hepatitis B vaccine; 1215 and 1209 received, respectively, the second and third doses. Anti-hepatitis B surface antigen (anti-HBs) values were studied in 406 subjects one month after the third dose, and 21 out of 406 (5.2%) had anti-HBs values less than 10 IU/L. We consider 95% of subjects with anti-HBs values greater than 9 IU/L a good achievement for a field vaccination program. 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In order to evaluate logistic problems and acceptance rate of adolescents to mass vaccination against hepatitis B, a pilot study was carried out among all 7th grade children registered in the 9 schools of an hepatitis B endemic area located in the suburbs of Naples. After meetings held by the local health department with school teachers and parents, 1219 out of 1250 (97.5%) invited children received the first dose of hepatitis B vaccine; 1215 and 1209 received, respectively, the second and third doses. Anti-hepatitis B surface antigen (anti-HBs) values were studied in 406 subjects one month after the third dose, and 21 out of 406 (5.2%) had anti-HBs values less than 10 IU/L. We consider 95% of subjects with anti-HBs values greater than 9 IU/L a good achievement for a field vaccination program. 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The high acceptance rate of vaccination found in our study outlines the importance of active offer of vaccination combined with school involvement.</abstract><cop>Dordrecht</cop><pub>Kluwer Academic Publishers</pub><pmid>8405316</pmid><doi>10.1007/BF00146268</doi><tpages>4</tpages></addata></record>
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subjects Adolescent
Adolescent Health Services - organization & administration
Adolescents
Age Factors
Age groups
Biological and medical sciences
Child
Children
Dosage
Epidemiology
Hepatitis B
Hepatitis B - blood
Hepatitis B - epidemiology
Hepatitis B - immunology
Hepatitis B - prevention & control
Hepatitis B - transmission
Hepatitis B Surface Antigens - blood
Hepatitis B virus
Human viral diseases
Humans
Immunization
Immunization Programs - organization & administration
Immunization Schedule
Infections
Infectious diseases
Italy - epidemiology
Mass Screening
Medical sciences
Patient Acceptance of Health Care
Pilot Projects
Population Surveillance
Prevalence
Risk Factors
School Health Services - organization & administration
Seroepidemiologic Studies
Sexual Behavior
Suburban Population
Vaccination
Viral diseases
Viral hepatitis
title Hepatitis B Mass Immunization of Adolescents: A Pilot Study in a Community
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