Does Ozone Alleviate AIDS Diarrhea?
Five patients with acquired immune deficiency syndrome (AIDS) or AIDS-related complex (ARC) and intractable diarrhea were treated with daily colonic insufflations of medical ozone (oxygen/ozone mixture) for 21–28 days. The daily dose of ozone (O3) ranged from 2.7 to 30 mg. Three of the four patients...
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| Veröffentlicht in: | Journal of clinical gastroenterology 1993-09, Vol.17 (2), p.142-145 |
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| container_title | Journal of clinical gastroenterology |
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| creator | Carpendale, Michael T Freeberg, Joel Griffiss, John McLeod |
| description | Five patients with acquired immune deficiency syndrome (AIDS) or AIDS-related complex (ARC) and intractable diarrhea were treated with daily colonic insufflations of medical ozone (oxygen/ozone mixture) for 21–28 days. The daily dose of ozone (O3) ranged from 2.7 to 30 mg. Three of the four patients whose diarrhea was of unknown etiology experienced complete resolution, and one patient had marked improvement. The fifth patient, whose diarrhea was due to Cryptosporidium, experienced no change. No consistent change in the absolute number of helper (CD4) or suppressor (CDS) lymphocytes was detected, and no obvious changes were seen in the Po2 or the results of routine hematologic and blood chemistry studies. Patients had mild to moderate local discomfort during ozone administration early in the course of treatment, but no adverse systemic effects were observed. The results of this series suggest that medical ozone administered by rectal insufflation is simple, safe, and effective. Should this simple treatment be used routinely to treat chronic intractable ARC/AIDS diarrhea? |
| doi_str_mv | 10.1097/00004836-199309000-00010 |
| format | Article |
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The daily dose of ozone (O3) ranged from 2.7 to 30 mg. Three of the four patients whose diarrhea was of unknown etiology experienced complete resolution, and one patient had marked improvement. The fifth patient, whose diarrhea was due to Cryptosporidium, experienced no change. No consistent change in the absolute number of helper (CD4) or suppressor (CDS) lymphocytes was detected, and no obvious changes were seen in the Po2 or the results of routine hematologic and blood chemistry studies. Patients had mild to moderate local discomfort during ozone administration early in the course of treatment, but no adverse systemic effects were observed. The results of this series suggest that medical ozone administered by rectal insufflation is simple, safe, and effective. Should this simple treatment be used routinely to treat chronic intractable ARC/AIDS diarrhea?</description><identifier>ISSN: 0192-0790</identifier><identifier>EISSN: 1539-2031</identifier><identifier>DOI: 10.1097/00004836-199309000-00010</identifier><identifier>PMID: 8409316</identifier><identifier>CODEN: JCGADC</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott-Raven Publishers</publisher><subject>Acquired Immunodeficiency Syndrome - complications ; Administration, Rectal ; Adult ; AIDS/HIV ; Biological and medical sciences ; Diarrhea - microbiology ; Diarrhea - therapy ; Humans ; Immunodeficiencies ; Immunodeficiencies. 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The daily dose of ozone (O3) ranged from 2.7 to 30 mg. Three of the four patients whose diarrhea was of unknown etiology experienced complete resolution, and one patient had marked improvement. The fifth patient, whose diarrhea was due to Cryptosporidium, experienced no change. No consistent change in the absolute number of helper (CD4) or suppressor (CDS) lymphocytes was detected, and no obvious changes were seen in the Po2 or the results of routine hematologic and blood chemistry studies. Patients had mild to moderate local discomfort during ozone administration early in the course of treatment, but no adverse systemic effects were observed. The results of this series suggest that medical ozone administered by rectal insufflation is simple, safe, and effective. Should this simple treatment be used routinely to treat chronic intractable ARC/AIDS diarrhea?</description><subject>Acquired Immunodeficiency Syndrome - complications</subject><subject>Administration, Rectal</subject><subject>Adult</subject><subject>AIDS/HIV</subject><subject>Biological and medical sciences</subject><subject>Diarrhea - microbiology</subject><subject>Diarrhea - therapy</subject><subject>Humans</subject><subject>Immunodeficiencies</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Ozone - administration & dosage</subject><subject>Ozone - therapeutic use</subject><subject>Pilot Projects</subject><subject>Treatment Outcome</subject><issn>0192-0790</issn><issn>1539-2031</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kd1LwzAQwIMoc07_BKGg-FbNR9vknmSsfgwGe1CfQ5akrJqtM2kd-tcbXd2bgZA77nd38AtCCcHXBAO_wfFkghUpAWAYYpbGS_ABGpKcQUoxI4doiAnQFHPAx-gkhNdIcMbIAA1EhoGRYoguysaGZP7VrG0yds5-1KqN0bR8Sspaeb-06vYUHVXKBXvWvyP0cn_3PHlMZ_OH6WQ8SzWL81JBiF4IDIIKUVFFARsojMhproq8YpoabY2mgoMWxBKtuWIV1qYyWjMDgo3Q1W7uxjfvnQ2tXNVBW-fU2jZdkDwH4BzzCIodqH0TgreV3Ph6pfynJFj--JF_fuTej_z1E1vP-x3dYmXNvrEXEuuXfV0FrVzl1VrXYY9lQGguIGLZDts2rrU-vLlua72Mtly7lP_9DvsGUTl6Cw</recordid><startdate>199309</startdate><enddate>199309</enddate><creator>Carpendale, Michael T</creator><creator>Freeberg, Joel</creator><creator>Griffiss, John McLeod</creator><general>Lippincott-Raven Publishers</general><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>8BM</scope></search><sort><creationdate>199309</creationdate><title>Does Ozone Alleviate AIDS Diarrhea?</title><author>Carpendale, Michael T ; Freeberg, Joel ; Griffiss, John McLeod</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3840-811cb8098288f2a290d96d8525a65f3c2dcedc2879c81e1cc7a3f0cdfdcc3d983</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Acquired Immunodeficiency Syndrome - complications</topic><topic>Administration, Rectal</topic><topic>Adult</topic><topic>AIDS/HIV</topic><topic>Biological and medical sciences</topic><topic>Diarrhea - microbiology</topic><topic>Diarrhea - therapy</topic><topic>Humans</topic><topic>Immunodeficiencies</topic><topic>Immunodeficiencies. Immunoglobulinopathies</topic><topic>Immunopathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Ozone - administration & dosage</topic><topic>Ozone - therapeutic use</topic><topic>Pilot Projects</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Carpendale, Michael T</creatorcontrib><creatorcontrib>Freeberg, Joel</creatorcontrib><creatorcontrib>Griffiss, John McLeod</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><jtitle>Journal of clinical gastroenterology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Carpendale, Michael T</au><au>Freeberg, Joel</au><au>Griffiss, John McLeod</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Does Ozone Alleviate AIDS Diarrhea?</atitle><jtitle>Journal of clinical gastroenterology</jtitle><addtitle>J Clin Gastroenterol</addtitle><date>1993-09</date><risdate>1993</risdate><volume>17</volume><issue>2</issue><spage>142</spage><epage>145</epage><pages>142-145</pages><issn>0192-0790</issn><eissn>1539-2031</eissn><coden>JCGADC</coden><abstract>Five patients with acquired immune deficiency syndrome (AIDS) or AIDS-related complex (ARC) and intractable diarrhea were treated with daily colonic insufflations of medical ozone (oxygen/ozone mixture) for 21–28 days. The daily dose of ozone (O3) ranged from 2.7 to 30 mg. Three of the four patients whose diarrhea was of unknown etiology experienced complete resolution, and one patient had marked improvement. The fifth patient, whose diarrhea was due to Cryptosporidium, experienced no change. No consistent change in the absolute number of helper (CD4) or suppressor (CDS) lymphocytes was detected, and no obvious changes were seen in the Po2 or the results of routine hematologic and blood chemistry studies. Patients had mild to moderate local discomfort during ozone administration early in the course of treatment, but no adverse systemic effects were observed. The results of this series suggest that medical ozone administered by rectal insufflation is simple, safe, and effective. Should this simple treatment be used routinely to treat chronic intractable ARC/AIDS diarrhea?</abstract><cop>Hagerstown, MD</cop><pub>Lippincott-Raven Publishers</pub><pmid>8409316</pmid><doi>10.1097/00004836-199309000-00010</doi><tpages>4</tpages></addata></record> |
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| ispartof | Journal of clinical gastroenterology, 1993-09, Vol.17 (2), p.142-145 |
| issn | 0192-0790 1539-2031 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Acquired Immunodeficiency Syndrome - complications Administration, Rectal Adult AIDS/HIV Biological and medical sciences Diarrhea - microbiology Diarrhea - therapy Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Male Medical sciences Middle Aged Ozone - administration & dosage Ozone - therapeutic use Pilot Projects Treatment Outcome |
| title | Does Ozone Alleviate AIDS Diarrhea? |
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