Geographic variations in Wilson's disease

Certain features of Wilson's disease (WD) in Asia have been found to be different from those in other continents. The higher prevalence rate in Japan is presumably due to a higher consanguinity rate. In Chinese there is a tight linkage between WD and two gene loci for esterase D and retinoblast...

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Veröffentlicht in:	Journal of the Neurological Sciences 1993-07, Vol.117 (1), p.1-7
Hauptverfasser:	Chu, Nai-Shin, Hung, Tsu-Pei
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Brain Diseases, Metabolic - etiology Brain Diseases, Metabolic - physiopathology Carcinoma, Hepatocellular - epidemiology China - epidemiology Comorbidity Consanguinity Copper - metabolism Disease Susceptibility Electroencephalography Electrophysiological investigation Ethnic Groups - genetics Europe - epidemiology Female Gene Frequency Genes, Recessive Genetic pattern Geographic variation Hepatitis B - epidemiology Hepatolenticular Degeneration - complications Hepatolenticular Degeneration - drug therapy Hepatolenticular Degeneration - epidemiology Hepatolenticular Degeneration - ethnology Hepatolenticular Degeneration - genetics Humans Incidence India - epidemiology Japan - epidemiology Liver Neoplasms - epidemiology Male Medical sciences Metabolic diseases Metals (hemochromatosis...) Other metabolic disorders Penicillamine - therapeutic use Phenotype Pregnancy Pregnancy Complications - drug therapy Prevalence Socio-economic problems Socioeconomic Factors White matter degeneration Wilson's disease
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