Complete Freund's adjuvant induces an earlier and more severe arthritis in MRL-lpr mice

A study was performed on the effect of CFA on the spontaneous arthritis of MRL-lpr mice. The development of swelling and erythema was monitored for 1 mo after injecting 13- to 14-wk-old mice intradermally with CFA, at which time the histopathology of the joints and serologic responses to extracellul...

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Veröffentlicht in:	The Journal of immunology (1950) 1993-11, Vol.151 (9), p.5081-5087
Hauptverfasser:	Ratkay, LG, Zhang, L, Tonzetich, J, Waterfield, JD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthritis, Experimental - etiology Arthritis, Experimental - pathology Arthritis, Rheumatoid - etiology Arthritis, Rheumatoid - pathology Autoimmune Diseases - complications Biological and medical sciences Disease Models, Animal Diseases of the osteoarticular system Female Freund's Adjuvant - immunology Interleukin-1 - pharmacology Lymphoproliferative Disorders - complications Male Medical sciences Mice Miscellaneous. Osteoarticular involvement in other diseases
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