Major histocompatibility complex-linked control of the murine immune response to myelin basic protein

Recent experiments have shown that different regions of myelin basic protein (MBP) are encephalitogenic for different inbred strains of mice. It was therefore of interest to determine whether the immune response to MBP was MHC associated, and if so, what subregion controlled this response. Because P...

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Veröffentlicht in:	The Journal of immunology (1950) 1985-04, Vol.134 (4), p.2328-2332
Hauptverfasser:	Fritz, RB, Skeen, MJ, Chou, CH, Garcia, M, Egorov, IK
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Autoantibodies - biosynthesis Biological and medical sciences Encephalomyelitis, Autoimmune, Experimental - genetics Encephalomyelitis, Autoimmune, Experimental - immunology Genes, MHC Class II H-2 Antigens - genetics H-2 Antigens - immunology Immunity, Innate Medical sciences Mice Mice, Inbred A Mice, Inbred C57BL Myelin Basic Protein - administration & dosage Myelin Basic Protein - immunology Nervous system involvement in other diseases. Miscellaneous Neurology Peptide Fragments - immunology Species Specificity
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