The Impact of Generalized Malignant Melanoma on Quality of Life Evaluated by the EORTC Questionnaire Technique
Eighty-nine patients with generalized malignant melanoma, 63% men and median age 53 years, were included in a longitudinal quality of life (QOL) study before the start of chemotherapy. QOL was assessed by the EORTC core questionnaire technique (QLQ-C36), a study-specific melanoma (MM) module and the...
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| Veröffentlicht in: | Quality of life research 1993-06, Vol.2 (3), p.193-203 |
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| creator | V. Sigurdardóttir C. Bolund Y. Brandberg Sullivan, M. |
| description | Eighty-nine patients with generalized malignant melanoma, 63% men and median age 53 years, were included in a longitudinal quality of life (QOL) study before the start of chemotherapy. QOL was assessed by the EORTC core questionnaire technique (QLQ-C36), a study-specific melanoma (MM) module and the Hospital Anxiety and Depression (HAD) scale. The questionnaires displayed good psychometric qualities and were able to document the florid symptomatology of disseminated melanoma. They were well accepted by the patients. Before treatment the patients reported a relatively low symptom burden, good physical and social functioning, moderate psychological distress and a high overall QOL rating during the past week. Fatigue and pain were the most frequent symptoms reported. The QOL measurement differentiated between subgroups of patients differing in performance status and the tumour burden. We conclude that the EORTC questionnaire technique is feasible and clinically relevant in generalized malignant melanoma patients. |
| doi_str_mv | 10.1007/BF00435223 |
| format | Article |
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Before treatment the patients reported a relatively low symptom burden, good physical and social functioning, moderate psychological distress and a high overall QOL rating during the past week. Fatigue and pain were the most frequent symptoms reported. The QOL measurement differentiated between subgroups of patients differing in performance status and the tumour burden. We conclude that the EORTC questionnaire technique is feasible and clinically relevant in generalized malignant melanoma patients.</description><subject>Activities of Daily Living</subject><subject>Adult</subject><subject>Aged</subject><subject>Anxiety - epidemiology</subject><subject>Anxiety - psychology</subject><subject>Cancer</subject><subject>Chemotherapy</subject><subject>Clinical trials</subject><subject>Depression - epidemiology</subject><subject>Depression - psychology</subject><subject>Depressive disorders</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Humans</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Melanoma</subject><subject>Melanoma - complications</subject><subject>Melanoma - physiopathology</subject><subject>Melanoma - psychology</subject><subject>Mental Health</subject><subject>Middle Aged</subject><subject>Oncology</subject><subject>Pain</subject><subject>Psychometrics</subject><subject>Quality of Life</subject><subject>Questionnaires</subject><subject>Reproducibility of Results</subject><subject>Surveys and Questionnaires - standards</subject><issn>0962-9343</issn><issn>1573-2649</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM1Lw0AQxRdRaq1ePCvsyYMQnf3I11FLW4WWotRzmCYTm5Js2mwi1L_eLS31NPDej8e8x9itgCcBED6_jgG08qVUZ6wv_FB5MtDxOetDHEgvVlpdsitr1wAQxSB7rBdpENr3-8wsVsTfqw2mLa9zPiFDDZbFL2V85u63QdPyGZVo6gp5bfhH5-R2t4enRU589INlh63jlzveurDR_HMxdBjZtqiNwaIhvqB0ZYptR9fsIsfS0s3xDtjXeLQYvnnT-eR9-DL1UgWq9XLlR0KCyEQWhIABSiV1FGqKl1mGIsdcYJCSlhgpp9DSlZFZGukYtQ41qgF7OORumnq7fyWpCptS6XpQ3dkk9OMoipXvwMcDmDa1tQ3lyaYpKmx2iYBkP27yP66D74-p3bKi7IQe13T-3cFf27ZuTrYGpX2Q6g8XUn1I</recordid><startdate>19930601</startdate><enddate>19930601</enddate><creator>V. 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Sigurdardóttir</creatorcontrib><creatorcontrib>C. Bolund</creatorcontrib><creatorcontrib>Y. Brandberg</creatorcontrib><creatorcontrib>Sullivan, M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Quality of life research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>V. Sigurdardóttir</au><au>C. Bolund</au><au>Y. Brandberg</au><au>Sullivan, M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Impact of Generalized Malignant Melanoma on Quality of Life Evaluated by the EORTC Questionnaire Technique</atitle><jtitle>Quality of life research</jtitle><addtitle>Qual Life Res</addtitle><date>1993-06-01</date><risdate>1993</risdate><volume>2</volume><issue>3</issue><spage>193</spage><epage>203</epage><pages>193-203</pages><issn>0962-9343</issn><eissn>1573-2649</eissn><abstract>Eighty-nine patients with generalized malignant melanoma, 63% men and median age 53 years, were included in a longitudinal quality of life (QOL) study before the start of chemotherapy. QOL was assessed by the EORTC core questionnaire technique (QLQ-C36), a study-specific melanoma (MM) module and the Hospital Anxiety and Depression (HAD) scale. The questionnaires displayed good psychometric qualities and were able to document the florid symptomatology of disseminated melanoma. 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| ispartof | Quality of life research, 1993-06, Vol.2 (3), p.193-203 |
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| subjects | Activities of Daily Living Adult Aged Anxiety - epidemiology Anxiety - psychology Cancer Chemotherapy Clinical trials Depression - epidemiology Depression - psychology Depressive disorders Feasibility Studies Female Humans Longitudinal Studies Male Melanoma Melanoma - complications Melanoma - physiopathology Melanoma - psychology Mental Health Middle Aged Oncology Pain Psychometrics Quality of Life Questionnaires Reproducibility of Results Surveys and Questionnaires - standards |
| title | The Impact of Generalized Malignant Melanoma on Quality of Life Evaluated by the EORTC Questionnaire Technique |
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