Role of a novel zebrafish nup98 during embryonic development

Objective The nucleoporin NUP98 is a component of the nuclear pore complex that regulates nucleocytoplasmic trafficking. It has been characterized in acute myeloid leukemia as a fusion partner during chromosomal translocation. In this study, we identified a zebrafish nup98 gene and examined its role...

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Veröffentlicht in:	Experimental hematology 2010-11, Vol.38 (11), p.1014-1021.e2
Hauptverfasser:	Fung, Tsz-Kan, Chung, Martin I.S, Liang, Raymond, Leung, Anskar Y.H
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Amino Acid Sequence Animals Animals, Genetically Modified Cloning, Molecular Embryo, Nonmammalian - embryology Embryo, Nonmammalian - metabolism Gene Expression Regulation, Developmental Genetic Complementation Test Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism HeLa Cells Hematology, Oncology and Palliative Medicine Humans Immunoblotting In Situ Hybridization Microscopy, Fluorescence Molecular Sequence Data Nuclear Pore Complex Proteins - genetics Nuclear Pore Complex Proteins - metabolism Nuclear Pore Complex Proteins - physiology Reverse Transcriptase Polymerase Chain Reaction RNA Interference RNA Transport RNA, Messenger - genetics RNA, Messenger - metabolism Sequence Analysis, DNA Sequence Homology, Amino Acid Zebrafish - embryology Zebrafish - genetics Zebrafish Proteins - genetics Zebrafish Proteins - metabolism Zebrafish Proteins - physiology
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