Regulation and Function of Insulin-Like Growth Factor-Binding Protein-1

Abstract Insulin-like growth factor-binding protein (IGFBP)-1 is one of six structurally homologous proteins that specifically bind and modulate the mitogenic and metabolic actions of insulin-like growth factor (IGF)-I and IGF-II. Of the six IGFBP, IGFBP-1 is the only one that displays rapid dynamic...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1993-10, Vol.204 (1), p.4-29
Hauptverfasser:	Lee, Phillip D. K., Conover, Cheryl A., Powell, David R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Biological and medical sciences Carrier Proteins - physiology Cattle Cyclic AMP - physiology Endocrine pancreas Female Fundamental and applied biological sciences. Psychology Gene Expression Genes Glucagon - physiology Glucocorticoids - pharmacology Growth Hormone - pharmacology Hepatectomy Hormones. Régulation Humans Insulin - physiology Insulin-Like Growth Factor Binding Proteins Insulin-Like Growth Factor I - physiology Molecular Sequence Data Oligopeptides Phylogeny Pregnancy Protein Kinase C - physiology Rats RNA, Messenger - genetics Sequence Alignment Sequence Homology, Amino Acid Theophylline - pharmacology Uterus - physiology Vertebrates: endocrinology
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