NEW PATCH DELIVERY SYSTEM FOR PERCUTANEOUS LOCAL ANAESTHESIA

We have assessed the release of amethocaine from a new patch delivery system and subsequent drug diffusion through human stratum corneum and whole skin. We found that the patch system was more efficient than an amethocaine gel preparation. It was also observed, both in vitro and in vivo, that the st...

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Veröffentlicht in:	British journal of anaesthesia : BJA 1993-09, Vol.71 (3), p.370-374
Hauptverfasser:	McCAFFERTY, D.F., WOOLFSON, A.D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Adult Anaesthetics Anaesthetics, local: amethocaine, EMLA Anesthesia, Local - methods Anesthetics, Local Anesthetics. Neuromuscular blocking agents Biological and medical sciences Double-Blind Method Drug Combinations EMLA Female Gels Humans Lidocaine - pharmacology Lidocaine, Prilocaine Drug Combination local: amethocaine Male Medical sciences Neuropharmacology Pharmacology. Drug treatments Prilocaine - pharmacology Skin - metabolism Tetracaine - administration & dosage Tetracaine - pharmacokinetics Tetracaine - pharmacology
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