The NS 3 Nonstructural Protein of Flaviviruses Contains an RNA Triphosphatase Activity

The genome of flaviviruses consists of an infectious single-stranded RNA molecule which contains a type 1 cap structure at the 5′-terminus. The cap is synthesized by RNA triphosphatase, guanylyltransferase and methyltransferase. Since flaviviruses replicate in the cytoplasm, it can be assumed that t...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 1993-11, Vol.197 (1), p.265-273
Hauptverfasser:	Wengler, Gerd, Wengler, Gisela
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Anhydride Hydrolases - chemistry Acid Anhydride Hydrolases - isolation & purification Acid Anhydride Hydrolases - metabolism Amino Acid Sequence Animals Biological and medical sciences Cell Line Chromatography, DEAE-Cellulose Chromatography, Gel Chromatography, Ion Exchange Edetic Acid - pharmacology flavivirus Flavivirus - enzymology Flavivirus - metabolism Fundamental and applied biological sciences. Psychology Kinetics Microbiology Molecular Sequence Data Morphology, structure, chemical composition, physicochemical properties Poly A - metabolism Sequence Homology, Amino Acid Time Factors Viral Nonstructural Proteins - chemistry Viral Nonstructural Proteins - isolation & purification Viral Nonstructural Proteins - metabolism Virology
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