Analysis of leukotrienes, prostaglandins, thromboxane B2 and their metabolites by capillary isotachophoresis
An analytical capillary isotachophoretic method for the analysis of the eicosanoids leukotriene E4, leukotriene B4, prostaglandins E1 and E2, 6‐keto‐prostaglandin F1α, thromboxane B2, and their metabolites of ω‐ and/or β‐oxidation is described. The method is based on anionic separation and detection...
Gespeichert in:
| Veröffentlicht in: | Electrophoresis 1993-07, Vol.14 (1), p.664-666 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 666 |
|---|---|
| container_issue | 1 |
| container_start_page | 664 |
| container_title | Electrophoresis |
| container_volume | 14 |
| creator | Tsikas, Dimitrios Fauler, Joachim Bracht, Stefan Brunner, Gorig Frölich, Jürgen C. |
| description | An analytical capillary isotachophoretic method for the analysis of the eicosanoids leukotriene E4, leukotriene B4, prostaglandins E1 and E2, 6‐keto‐prostaglandin F1α, thromboxane B2, and their metabolites of ω‐ and/or β‐oxidation is described. The method is based on anionic separation and detection by UV absorbance (254 nm) and conductivity and allows simultaneous analysis of the primary compounds and their corresponding major urinary metabolites. The method was applicable to the qualitative and quantitative analysis of prostaglandin E1 in a drug preparation. |
| doi_str_mv | 10.1002/elps.11501401104 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_75964681</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>75964681</sourcerecordid><originalsourceid>FETCH-LOGICAL-i3274-8f75341717f68623e0886d6a9c6f2aa4a1309de8ba17caca068303de57289ab43</originalsourceid><addsrcrecordid>eNpNkc1v1DAQxS0EKtvCnQtSDogTKeOP2M6BQ2lLAa0AifJxsybZCWvqxCHOqt3_Hle7WvVkzbzfs2f8GHvB4ZQDiLcUxnTKeQVcAeegHrEFr4QohbbyMVsAN7IEK6un7DilvwCgaqWO2JGVtQErFiycDRi2yacidkWgzU2cJ08DpTfFOMU045-Aw8oPuZ7XU-ybeIcDFe9Fkdu5RX4qepqxicHPlIpmW7Q4-hBw2hY-xRnbdRzXcaL8xjP2pMOQ6Pn-PGE_Plxen38sl1-vPp2fLUsvhVGl7UwlFTfcdNpqIQms1SuNdas7gaiQS6hXZBvkpsUWIS8LckWVEbbGRskT9np3b17h34bS7HqfWspDDRQ3yZmq1kpbnsGXe3DT9LRy4-T7PLjbf0_WX-11TC2GbsKh9emASWO4FTZj73bYrQ-0Pcgc3H1I7j4k9yAkd7n89v1Bnf3lzu_TTHcHP043ThtpKvfry5WD68_6988LcBfyP1T0lsE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>75964681</pqid></control><display><type>article</type><title>Analysis of leukotrienes, prostaglandins, thromboxane B2 and their metabolites by capillary isotachophoresis</title><source>MEDLINE</source><source>Wiley Journals</source><creator>Tsikas, Dimitrios ; Fauler, Joachim ; Bracht, Stefan ; Brunner, Gorig ; Frölich, Jürgen C.</creator><creatorcontrib>Tsikas, Dimitrios ; Fauler, Joachim ; Bracht, Stefan ; Brunner, Gorig ; Frölich, Jürgen C.</creatorcontrib><description>An analytical capillary isotachophoretic method for the analysis of the eicosanoids leukotriene E4, leukotriene B4, prostaglandins E1 and E2, 6‐keto‐prostaglandin F1α, thromboxane B2, and their metabolites of ω‐ and/or β‐oxidation is described. The method is based on anionic separation and detection by UV absorbance (254 nm) and conductivity and allows simultaneous analysis of the primary compounds and their corresponding major urinary metabolites. The method was applicable to the qualitative and quantitative analysis of prostaglandin E1 in a drug preparation.</description><identifier>ISSN: 0173-0835</identifier><identifier>EISSN: 1522-2683</identifier><identifier>DOI: 10.1002/elps.11501401104</identifier><identifier>PMID: 8397082</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>6-Ketoprostaglandin F1 alpha - analysis ; 6-Ketoprostaglandin F1 alpha - urine ; Alprostadil - analysis ; Alprostadil - urine ; Analytical, structural and metabolic biochemistry ; Biological and medical sciences ; Capillary Action ; Dinoprostone - analysis ; Dinoprostone - urine ; Electrophoresis - methods ; Fatty acids ; Fundamental and applied biological sciences. Psychology ; Leukotriene B4 - analysis ; Leukotriene E4 ; Leukotrienes - analysis ; Leukotrienes - urine ; Lipids ; Other biological molecules ; Oxidation-Reduction ; Prostaglandins - analysis ; Prostaglandins - urine ; SRS-A - analogs & derivatives ; SRS-A - analysis ; Thromboxane B2 - analysis ; Thromboxane B2 - urine</subject><ispartof>Electrophoresis, 1993-07, Vol.14 (1), p.664-666</ispartof><rights>Copyright © 1993 VCH Verlagsgesellschaft mbH</rights><rights>1994 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Felps.11501401104$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Felps.11501401104$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3771828$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8397082$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tsikas, Dimitrios</creatorcontrib><creatorcontrib>Fauler, Joachim</creatorcontrib><creatorcontrib>Bracht, Stefan</creatorcontrib><creatorcontrib>Brunner, Gorig</creatorcontrib><creatorcontrib>Frölich, Jürgen C.</creatorcontrib><title>Analysis of leukotrienes, prostaglandins, thromboxane B2 and their metabolites by capillary isotachophoresis</title><title>Electrophoresis</title><addtitle>ELECTROPHORESIS</addtitle><description>An analytical capillary isotachophoretic method for the analysis of the eicosanoids leukotriene E4, leukotriene B4, prostaglandins E1 and E2, 6‐keto‐prostaglandin F1α, thromboxane B2, and their metabolites of ω‐ and/or β‐oxidation is described. The method is based on anionic separation and detection by UV absorbance (254 nm) and conductivity and allows simultaneous analysis of the primary compounds and their corresponding major urinary metabolites. The method was applicable to the qualitative and quantitative analysis of prostaglandin E1 in a drug preparation.</description><subject>6-Ketoprostaglandin F1 alpha - analysis</subject><subject>6-Ketoprostaglandin F1 alpha - urine</subject><subject>Alprostadil - analysis</subject><subject>Alprostadil - urine</subject><subject>Analytical, structural and metabolic biochemistry</subject><subject>Biological and medical sciences</subject><subject>Capillary Action</subject><subject>Dinoprostone - analysis</subject><subject>Dinoprostone - urine</subject><subject>Electrophoresis - methods</subject><subject>Fatty acids</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Leukotriene B4 - analysis</subject><subject>Leukotriene E4</subject><subject>Leukotrienes - analysis</subject><subject>Leukotrienes - urine</subject><subject>Lipids</subject><subject>Other biological molecules</subject><subject>Oxidation-Reduction</subject><subject>Prostaglandins - analysis</subject><subject>Prostaglandins - urine</subject><subject>SRS-A - analogs & derivatives</subject><subject>SRS-A - analysis</subject><subject>Thromboxane B2 - analysis</subject><subject>Thromboxane B2 - urine</subject><issn>0173-0835</issn><issn>1522-2683</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkc1v1DAQxS0EKtvCnQtSDogTKeOP2M6BQ2lLAa0AifJxsybZCWvqxCHOqt3_Hle7WvVkzbzfs2f8GHvB4ZQDiLcUxnTKeQVcAeegHrEFr4QohbbyMVsAN7IEK6un7DilvwCgaqWO2JGVtQErFiycDRi2yacidkWgzU2cJ08DpTfFOMU045-Aw8oPuZ7XU-ybeIcDFe9Fkdu5RX4qepqxicHPlIpmW7Q4-hBw2hY-xRnbdRzXcaL8xjP2pMOQ6Pn-PGE_Plxen38sl1-vPp2fLUsvhVGl7UwlFTfcdNpqIQms1SuNdas7gaiQS6hXZBvkpsUWIS8LckWVEbbGRskT9np3b17h34bS7HqfWspDDRQ3yZmq1kpbnsGXe3DT9LRy4-T7PLjbf0_WX-11TC2GbsKh9emASWO4FTZj73bYrQ-0Pcgc3H1I7j4k9yAkd7n89v1Bnf3lzu_TTHcHP043ThtpKvfry5WD68_6988LcBfyP1T0lsE</recordid><startdate>19930701</startdate><enddate>19930701</enddate><creator>Tsikas, Dimitrios</creator><creator>Fauler, Joachim</creator><creator>Bracht, Stefan</creator><creator>Brunner, Gorig</creator><creator>Frölich, Jürgen C.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-VCH</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19930701</creationdate><title>Analysis of leukotrienes, prostaglandins, thromboxane B2 and their metabolites by capillary isotachophoresis</title><author>Tsikas, Dimitrios ; Fauler, Joachim ; Bracht, Stefan ; Brunner, Gorig ; Frölich, Jürgen C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i3274-8f75341717f68623e0886d6a9c6f2aa4a1309de8ba17caca068303de57289ab43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>6-Ketoprostaglandin F1 alpha - analysis</topic><topic>6-Ketoprostaglandin F1 alpha - urine</topic><topic>Alprostadil - analysis</topic><topic>Alprostadil - urine</topic><topic>Analytical, structural and metabolic biochemistry</topic><topic>Biological and medical sciences</topic><topic>Capillary Action</topic><topic>Dinoprostone - analysis</topic><topic>Dinoprostone - urine</topic><topic>Electrophoresis - methods</topic><topic>Fatty acids</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Leukotriene B4 - analysis</topic><topic>Leukotriene E4</topic><topic>Leukotrienes - analysis</topic><topic>Leukotrienes - urine</topic><topic>Lipids</topic><topic>Other biological molecules</topic><topic>Oxidation-Reduction</topic><topic>Prostaglandins - analysis</topic><topic>Prostaglandins - urine</topic><topic>SRS-A - analogs & derivatives</topic><topic>SRS-A - analysis</topic><topic>Thromboxane B2 - analysis</topic><topic>Thromboxane B2 - urine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tsikas, Dimitrios</creatorcontrib><creatorcontrib>Fauler, Joachim</creatorcontrib><creatorcontrib>Bracht, Stefan</creatorcontrib><creatorcontrib>Brunner, Gorig</creatorcontrib><creatorcontrib>Frölich, Jürgen C.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Electrophoresis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tsikas, Dimitrios</au><au>Fauler, Joachim</au><au>Bracht, Stefan</au><au>Brunner, Gorig</au><au>Frölich, Jürgen C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Analysis of leukotrienes, prostaglandins, thromboxane B2 and their metabolites by capillary isotachophoresis</atitle><jtitle>Electrophoresis</jtitle><addtitle>ELECTROPHORESIS</addtitle><date>1993-07-01</date><risdate>1993</risdate><volume>14</volume><issue>1</issue><spage>664</spage><epage>666</epage><pages>664-666</pages><issn>0173-0835</issn><eissn>1522-2683</eissn><abstract>An analytical capillary isotachophoretic method for the analysis of the eicosanoids leukotriene E4, leukotriene B4, prostaglandins E1 and E2, 6‐keto‐prostaglandin F1α, thromboxane B2, and their metabolites of ω‐ and/or β‐oxidation is described. The method is based on anionic separation and detection by UV absorbance (254 nm) and conductivity and allows simultaneous analysis of the primary compounds and their corresponding major urinary metabolites. The method was applicable to the qualitative and quantitative analysis of prostaglandin E1 in a drug preparation.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>8397082</pmid><doi>10.1002/elps.11501401104</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0173-0835 |
| ispartof | Electrophoresis, 1993-07, Vol.14 (1), p.664-666 |
| issn | 0173-0835 1522-2683 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75964681 |
| source | MEDLINE; Wiley Journals |
| subjects | 6-Ketoprostaglandin F1 alpha - analysis 6-Ketoprostaglandin F1 alpha - urine Alprostadil - analysis Alprostadil - urine Analytical, structural and metabolic biochemistry Biological and medical sciences Capillary Action Dinoprostone - analysis Dinoprostone - urine Electrophoresis - methods Fatty acids Fundamental and applied biological sciences. Psychology Leukotriene B4 - analysis Leukotriene E4 Leukotrienes - analysis Leukotrienes - urine Lipids Other biological molecules Oxidation-Reduction Prostaglandins - analysis Prostaglandins - urine SRS-A - analogs & derivatives SRS-A - analysis Thromboxane B2 - analysis Thromboxane B2 - urine |
| title | Analysis of leukotrienes, prostaglandins, thromboxane B2 and their metabolites by capillary isotachophoresis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T11%3A25%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Analysis%20of%20leukotrienes,%20prostaglandins,%20thromboxane%20B2%20and%20their%20metabolites%20by%20capillary%20isotachophoresis&rft.jtitle=Electrophoresis&rft.au=Tsikas,%20Dimitrios&rft.date=1993-07-01&rft.volume=14&rft.issue=1&rft.spage=664&rft.epage=666&rft.pages=664-666&rft.issn=0173-0835&rft.eissn=1522-2683&rft_id=info:doi/10.1002/elps.11501401104&rft_dat=%3Cproquest_pubme%3E75964681%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=75964681&rft_id=info:pmid/8397082&rfr_iscdi=true |