CCAAT/Enhancer-Binding Protein mRNA is Translated into Multiple Proteins with Different Transcription Activation Potentials

The CCAAT/enhancer-binding protein (C/EBP) α is a leucine zipper protein that is preferentially expressed in certain cell types, such as adipocytes and hepatocytes. Here we show that C/EBP α mRNA is translated into two major proteins, C/EBP-42 and C/EBP-30, that differ in their content of N-terminal...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1993-09, Vol.90 (17), p.8219-8223
Hauptverfasser:	Ossipow, Vincent, Descombes, Patrick, Schibler, Ueli
Format:	Artikel
Sprache:	eng
Schlagworte:	Affinity Labels Albumins Amino Acid Sequence Animals Azides Base Sequence Biological and medical sciences CCAAT-Enhancer-Binding Proteins Conserved Sequence COS cells DNA DNA-Binding Proteins - biosynthesis DNA-Binding Proteins - isolation & purification DNA-Binding Proteins - metabolism Fundamental and applied biological sciences. Psychology Gels Genes Genetic Vectors Genetics Humans Liver Liver - metabolism Messenger RNA Molecular and cellular biology Molecular genetics Molecular Sequence Data Nuclear Proteins - biosynthesis Nuclear Proteins - isolation & purification Nuclear Proteins - metabolism Oligonucleotide Probes - chemical synthesis Protein Biosynthesis Proteins Rats Recombinant Proteins - biosynthesis Recombinant Proteins - metabolism Ribonucleic acid RNA RNA, Messenger - metabolism Species Specificity Transcription Factors - biosynthesis Transcription. Transcription factor. Splicing. Rna processing Transfection Uridine Triphosphate - analogs & derivatives Vertebrates Vertebrates - metabolism
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