Poststreptococcal Anti-Myosin Antibody Idiotype Associated with Systemic Lupus Erythematosus and Sjögren's Syndrome

Anti-myosin antibodies are found in acute rheumatic fever (ARF), a sequela of group A streptococcal infection. An antiidiotypic serum was produced that was specific for idiotopes expressed by anti-myosin antibodies in ARF (anti-My1). Studies indicated that idiotypic determinants detected with this s...

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Veröffentlicht in:	The Journal of infectious diseases 1993-10, Vol.168 (4), p.915-921
Hauptverfasser:	McCormack, Jeffrey M., Crossley, Carol A., Ayoub, Elia M., Harley, John B., Cunningham, Madeleine W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antiserum Autoantibodies - blood Autoimmune diseases Biological and medical sciences Enzyme-Linked Immunosorbent Assay Epitopes Glomerulonephritis Glomerulonephritis - blood Glomerulonephritis - etiology Glomerulonephritis - immunology Humans Immunoglobulin Idiotypes - blood Immunoglobulins Lupus Erythematosus, Systemic - blood Lupus Erythematosus, Systemic - immunology Major Articles Medical sciences Monoclonal antibodies Myosins - immunology Reactivity Rheumatic fever Rheumatic Fever - blood Rheumatic Fever - immunology Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Sjogren's Syndrome - blood Sjogren's Syndrome - immunology Streptococcal Infections - blood Streptococcal Infections - complications Streptococcal Infections - immunology Streptococcus pyogenes - isolation & purification Systemic lupus erythematosus
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