Cl − channels are randomly activated by continuous GABA secretion in cultured embryonic rat hippocampal neurons

Throughout the adult vertebrate central nervous system (CNS) γ-aminobutyric acid (GABA) mediates transient Cl − conductances commonly identified as fast, Cl −-dependent inhibitory synaptic signals [Prog. Neurobiol., 36 (1991) 35–92). In the rat hippocampus Cl −-dependent excitatory transients mediat...

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Veröffentlicht in:	Neuroscience letters 1993-06, Vol.155 (2), p.199-203
Hauptverfasser:	Valeyev, A.Y., Cruciani, R.A., Lange, G.D., Smallwood, V.S., Barker, J.L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - drug effects Animals Animals, Newborn Bicuculline Biological and medical sciences Cell Communication Cells, Cultured Chloride Channels Chlorides - metabolism Embryology: invertebrates and vertebrates. Teratology Embryonic hippocampal neuron Fundamental and applied biological sciences. Psychology GABA GABA A receptor gamma-Aminobutyric Acid - metabolism gamma-Aminobutyric Acid - pharmacology Hippocampus - cytology Hippocampus - embryology Hippocampus - growth & development Ion Channel Gating - drug effects Membrane Proteins - drug effects Membrane Proteins - metabolism Neurons - metabolism Organogenesis. Physiological fonctions Physiological fonctions Rats Receptors, GABA-A - drug effects Receptors, GABA-A - physiology Secretion Synaptic Transmission - drug effects
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