Determination of Auranofin, a Chrysotherapy Agent, in Urine by HPLC with a Postcolumn Reaction and Visible Detection

Auranofin [(2, 3, 4, 6-tetra-O-acetyl-1-thio-β-D-glucopyranosato-S)(triethylphosphine)gold(I) : AF] is a unique orally active chrysotherapy agent. A HPLC method has been developed for determining AF in urine. The proposed method comprises initial chromatographic separation of AF followed by on-line...

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