Medroxyprogesterone acetate inhibits the proliferation of estrogen- and progesterone-receptor negative MFM-223 human mammary cancer cells via the androgen receptor

This study demonstrates for the first time, that medroxyprogesterone acetate (MPA) inhibits the proliferation of the estrogen and progesterone receptor negative mammary cancer cell line MFM-223 via the androgen receptor. MPA is a progestin, which is used in the hormonal treatment of disseminated bre...

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Veröffentlicht in:	Breast cancer research and treatment 1993, Vol.25 (3), p.217-224
Hauptverfasser:	HACKENBERG, R, HAWIGHORST, T, FILMER, A, ABDOLHAMID HUSCHMAND NIA, SCHULZ, K.-D
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgen Receptor Antagonists Antineoplastic agents Biological and medical sciences Breast Neoplasms - chemistry Breast Neoplasms - pathology Cell Division - drug effects Chemotherapy Dexamethasone - pharmacology Dihydrotestosterone - pharmacology Female Humans Medical sciences Medroxyprogesterone Acetate - pharmacology Pharmacology. Drug treatments Tumor Cells, Cultured
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