Epidermal-growth-factor receptors and oestrogen receptors in human breast cancer

Competitive binding and monoclonal antibody staining techniques were used to demonstrate high-affinity (Kd = 1.9 nmol/l) receptors for epidermal growth factor (EGF) in 35 of 104 primary human breast tumours and in 10 of 14 secondary lymph-node deposits. There was a significant inverse relation betwe...

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Veröffentlicht in:	The Lancet (British edition) 1985-02, Vol.1 (8425), p.364-366
Hauptverfasser:	Sainsbury, J R, Farndon, J R, Sherbet, G V, Harris, A L
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast Neoplasms - metabolism Breast Neoplasms - pathology ErbB Receptors Female Humans Lymph Nodes - metabolism Lymphatic Metastasis Neoplasm Metastasis Receptors, Cell Surface - metabolism Receptors, Estrogen - metabolism
Online-Zugang:	Volltext
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