Galanin-containing fibers innervate substance P-containing neurons in the pedunculopontine tegmental nucleus in humans

Galanin is a putative peptide transmitter distributed widely in the central nervous system. Galanin shows potent inhibitory effects on neuronal activity and learning behaviors induced or mediated by acetylcholine. Here, we demonstrate that in humans there are abundant galanin-containing fibers in th...

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Veröffentlicht in:	Brain research 1993-07, Vol.618 (1), p.135-141
Hauptverfasser:	Gai, W.P., Blumbergs, P.C., Geffen, L.B., Blessing, W.W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Ascending reticular cholinergic system Biological and medical sciences Brain Stem - cytology Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Female Fundamental and applied biological sciences. Psychology Galanin Human brainstem Humans Male Middle Aged Nerve Fibers - chemistry Nerve Fibers - physiology Neurons - chemistry Neuropeptides - analysis Pedunculopontine tegmental nucleus Peptides - analysis Substance P Substance P - analysis Vertebrates: nervous system and sense organs
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