The role of the thymus in the maintenance of natural killer cells in vivo

This report describes a model for investigating the role of the thymus in regulating natural killer (NK) cell activity in vivo. Evidence is presented that the thymus can regulate NK cells, and that at least some NK cells can develop without thymic help. Marrow from thymectomized rats depleted of cir...

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Veröffentlicht in:	Cellular immunology 1985-02, Vol.90 (2), p.366-377
Hauptverfasser:	Flexman, J.P., Holt, P.G., Mayrhofer, G., Latham, B.I., Shellam, G.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Animals Biological and medical sciences Bone Marrow Transplantation Cell Differentiation Cytotoxicity, Immunologic Fundamental and applied biological sciences. Psychology Fundamental immunology Immunobiology Interferons - biosynthesis Killer Cells, Natural - cytology Killer Cells, Natural - immunology Killer Cells, Natural - physiology Lymphocyte Depletion Male Organs and cells involved in the immune response Radiation Chimera Rats Rats, Inbred Strains T-Lymphocytes - physiology Thymus Gland - physiology
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