Effects of Adoptive Immunotherapy with Autologous CD8 + T Lymphocytes on Immunologic Parameters: Lymphocyte Subsets and Cytotoxic Activity

CD8 + cytotoxic T lymphocytes (CTL) may be an important parameter of host resistance to HIV infection. The present study determined whether CD8 + cells could be purified and propagated in vitro to enhance anti-HIV CTL activity, and the immunologic effects of infusion of these cells into autologous,...

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Veröffentlicht in:	Clinical immunology and immunopathology 1993-09, Vol.68 (3), p.263-272
Hauptverfasser:	Torpey, David, Huang, Xiao-Li, Armstrong, John, Ho, Monto, Whiteside, Theresa, McMahon, Deborah, Pazin, George, Herberman, Ronald, Gupta, Phalguni, Tripoli, Christine, Moody, Dewey, Okarma, Thomas, Elder, Elaine, Rinaldo, Charles
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immunodeficiency Syndrome - therapy AIDS-Related Complex - therapy AIDS/HIV Biological and medical sciences CD8 Antigens - analysis Cytotoxicity, Immunologic Gene Expression HIV Antigens - immunology HIV-1 - genetics HIV-1 - immunology Humans Immunity, Cellular Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Immunotherapy, Adoptive Medical sciences T-Lymphocyte Subsets - immunology T-Lymphocytes, Cytotoxic - immunology
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