Familial IgA Nephropathy: Evidence of an Inherited Mechanism of Disease

The evaluation of familial glomerulonephritis in patients with IgA nephropathy who were from central and eastern Kentucky resulted in the discovery of potentially related pedigrees containing 14 patients. An additional 17 members of the pedigrees had clinical glomerulonephritis, and 6 had "chro...

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Veröffentlicht in:	The New England journal of medicine 1985-01, Vol.312 (4), p.202-208
Hauptverfasser:	Julian, Bruce A, Quiggins, Patricia A, Thompson, John S, Woodford, Susan Y, Gleason, Karen, Wyatt, Robert J
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Biological and medical sciences Biopsy Blood & organ donations Family medical history Female Glomerulonephritis Glomerulonephritis, IGA - genetics Haplotypes Histocompatibility antigen HLA Histocompatibility Antigens Class II - analysis HLA Antigens - analysis HLA-DR Antigens Humans IgA nephropathy Immunoglobulin A Kentucky Laboratories Male Medical sciences Medicine Microscopy Nephritis Nephrology Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Patients Pedigree Phenotype Population
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