Expression of GATA-2 in Human Pituitary Adenomas

Transcription factor GATA-2 contains two copies of a highly conserved zinc finger domain and plays unique roles at an early stage of hematopoietic differentiation. In the mouse pituitary gland, Pit-1-GATA-2 protein–protein interaction has been shown to lead to gene-specific actions to obtain cell-sp...

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Veröffentlicht in:	Modern pathology 2002-01, Vol.15 (1), p.11-17
Hauptverfasser:	Umeoka, Katsuya, Sanno, Naoko, Osamura, R Yoshiyuki, Teramoto, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - metabolism Adenoma - pathology Adult Aged DNA-Binding Proteins - biosynthesis DNA-Binding Proteins - genetics Female GATA-2 GATA2 Transcription Factor Gonadotropins - secretion Growth Hormone - secretion Growth hormones Humans Immunohistochemistry Imunohistochemistry Laboratory Medicine Male Medicine Medicine & Public Health Middle Aged original-article Pathology Pit-1 Pituitary adenoma Pituitary gland Pituitary Neoplasms - metabolism Pituitary Neoplasms - pathology Polymerase chain reaction Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism RNA, Neoplasm - analysis RT-PCR Thyroid gland Thyrotropin - secretion Transcription factor Transcription Factor Pit-1 Transcription factors Transcription Factors - biosynthesis Transcription Factors - genetics Tumors Zinc Fingers - genetics
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