Illicit drugs in wastewater of the city of Zagreb (Croatia) – Estimation of drug abuse in a transition country

A comprehensive study of various psychoactive substances and their metabolites was performed in the wastewater treatment plant of the city of Zagreb (780 000 inhabitants) using liquid chromatography/tandem mass spectrometry (LC–MS–MS). The estimation of drug abuse for five different illicit drugs, i...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Environmental pollution (1987) 2010-08, Vol.158 (8), p.2686-2693
Hauptverfasser: Terzic, Senka, Senta, Ivan, Ahel, Marijan
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 2693
container_issue 8
container_start_page 2686
container_title Environmental pollution (1987)
container_volume 158
creator Terzic, Senka
Senta, Ivan
Ahel, Marijan
description A comprehensive study of various psychoactive substances and their metabolites was performed in the wastewater treatment plant of the city of Zagreb (780 000 inhabitants) using liquid chromatography/tandem mass spectrometry (LC–MS–MS). The estimation of drug abuse for five different illicit drugs, including heroin, cocaine, marijuana, amphetamine and ecstasy, was made on the basis of their representative excretion rates, which were determined over a period of 8 months. Marijuana (1000 kg/year), heroin (75 kg/year) and cocaine (47 kg/year) were found to be the most frequently consumed illicit drugs, while the consumption of amphetamine-type drugs was much lower (1–3 kg/year). A comparison with other reports indicated that drug abuse profiles in transition countries might be different from those reported for Western Europe, in particular with respect to the comparatively increased consumption of heroin. Enhanced consumption of stimulating drugs (cocaine and ectasy) was systematically detected during weekends. Wastewater analysis is a promising complementary tool to assess drug abuse patterns.
doi_str_mv 10.1016/j.envpol.2010.04.020
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_759309251</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0269749110001727</els_id><sourcerecordid>759309251</sourcerecordid><originalsourceid>FETCH-LOGICAL-c522t-cad6ab1d4ed8c51edb2c5aaa3d903dc46329379b3805482685c3c24eaee4cdd13</originalsourceid><addsrcrecordid>eNqNkU1uFDEQhS0EIpPADRDyBhEWPZT_-mcTCY0CRIrEBjZsLLddEzzqaQ-2O9HsuAM3zElwMwPsIla2q756Zb1HyAsGSwasfrtZ4ni7C8OSQymBXAKHR2TB2kZUteTyMVkAr7uqkR07IacpbQBACiGekhMOikGpL8juahi89Zm6ON0k6kd6Z1LGO5Mx0rCm-RvS0t7P96_mJmJPz1cxmOzNG3r_4ye9TNlvyzOMMzKrUNNPCWcpQ3M0Y_K_uzZMY477Z-TJ2gwJnx_PM_Ll_eXn1cfq-tOHq9W768oqznNljatNz5xE11rF0PXcKmOMcB0IZ2UteCearhctKNnyulVWWC7RIErrHBNn5PVBdxfD9wlT1lufLA6DGTFMSTeqE9Bx9R-kEF0LTTOT5w-SrCkU8FZ2BZUH1MaQUsS13sXiU9xrBnrOT2_0IT8956dB6pJfGXt53DD1W3R_h_4EVoBXR8Aka4Z18df69I8TwKWCef_FgcPi8a3HqJP1OFp0PqLN2gX_8E9-AfNou6o</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1777102849</pqid></control><display><type>article</type><title>Illicit drugs in wastewater of the city of Zagreb (Croatia) – Estimation of drug abuse in a transition country</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Terzic, Senka ; Senta, Ivan ; Ahel, Marijan</creator><creatorcontrib>Terzic, Senka ; Senta, Ivan ; Ahel, Marijan</creatorcontrib><description>A comprehensive study of various psychoactive substances and their metabolites was performed in the wastewater treatment plant of the city of Zagreb (780 000 inhabitants) using liquid chromatography/tandem mass spectrometry (LC–MS–MS). The estimation of drug abuse for five different illicit drugs, including heroin, cocaine, marijuana, amphetamine and ecstasy, was made on the basis of their representative excretion rates, which were determined over a period of 8 months. Marijuana (1000 kg/year), heroin (75 kg/year) and cocaine (47 kg/year) were found to be the most frequently consumed illicit drugs, while the consumption of amphetamine-type drugs was much lower (1–3 kg/year). A comparison with other reports indicated that drug abuse profiles in transition countries might be different from those reported for Western Europe, in particular with respect to the comparatively increased consumption of heroin. Enhanced consumption of stimulating drugs (cocaine and ectasy) was systematically detected during weekends. Wastewater analysis is a promising complementary tool to assess drug abuse patterns.</description><identifier>ISSN: 0269-7491</identifier><identifier>EISSN: 1873-6424</identifier><identifier>DOI: 10.1016/j.envpol.2010.04.020</identifier><identifier>PMID: 20510491</identifier><identifier>CODEN: ENVPAF</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Amphetamines - analysis ; Applied sciences ; Cannabinoids - analysis ; Chromatography, Liquid ; Cities ; Cocaine - analysis ; Croatia ; Drug abuse ; Drug consumption ; Drugs ; Environmental Monitoring ; Epidemiological Monitoring ; Exact sciences and technology ; Excretion ; Heroin - analysis ; Illicit ; Illicit drugs ; Inhabitants ; LC–MS–MS ; Marijuana ; Municipal wastewater ; Other wastewaters ; Pollution ; Pollution abatement ; Street Drugs - analysis ; Substance-Related Disorders - epidemiology ; Tandem Mass Spectrometry ; Therapeutic opiates ; Waste Disposal, Fluid ; Waste water ; Wastewaters ; Water Pollutants, Chemical - analysis ; Water Pollution, Chemical - statistics &amp; numerical data ; Water treatment and pollution</subject><ispartof>Environmental pollution (1987), 2010-08, Vol.158 (8), p.2686-2693</ispartof><rights>2010 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright 2010 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c522t-cad6ab1d4ed8c51edb2c5aaa3d903dc46329379b3805482685c3c24eaee4cdd13</citedby><cites>FETCH-LOGICAL-c522t-cad6ab1d4ed8c51edb2c5aaa3d903dc46329379b3805482685c3c24eaee4cdd13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.envpol.2010.04.020$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27929,27930,46000</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=23024509$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20510491$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Terzic, Senka</creatorcontrib><creatorcontrib>Senta, Ivan</creatorcontrib><creatorcontrib>Ahel, Marijan</creatorcontrib><title>Illicit drugs in wastewater of the city of Zagreb (Croatia) – Estimation of drug abuse in a transition country</title><title>Environmental pollution (1987)</title><addtitle>Environ Pollut</addtitle><description>A comprehensive study of various psychoactive substances and their metabolites was performed in the wastewater treatment plant of the city of Zagreb (780 000 inhabitants) using liquid chromatography/tandem mass spectrometry (LC–MS–MS). The estimation of drug abuse for five different illicit drugs, including heroin, cocaine, marijuana, amphetamine and ecstasy, was made on the basis of their representative excretion rates, which were determined over a period of 8 months. Marijuana (1000 kg/year), heroin (75 kg/year) and cocaine (47 kg/year) were found to be the most frequently consumed illicit drugs, while the consumption of amphetamine-type drugs was much lower (1–3 kg/year). A comparison with other reports indicated that drug abuse profiles in transition countries might be different from those reported for Western Europe, in particular with respect to the comparatively increased consumption of heroin. Enhanced consumption of stimulating drugs (cocaine and ectasy) was systematically detected during weekends. Wastewater analysis is a promising complementary tool to assess drug abuse patterns.</description><subject>Amphetamines - analysis</subject><subject>Applied sciences</subject><subject>Cannabinoids - analysis</subject><subject>Chromatography, Liquid</subject><subject>Cities</subject><subject>Cocaine - analysis</subject><subject>Croatia</subject><subject>Drug abuse</subject><subject>Drug consumption</subject><subject>Drugs</subject><subject>Environmental Monitoring</subject><subject>Epidemiological Monitoring</subject><subject>Exact sciences and technology</subject><subject>Excretion</subject><subject>Heroin - analysis</subject><subject>Illicit</subject><subject>Illicit drugs</subject><subject>Inhabitants</subject><subject>LC–MS–MS</subject><subject>Marijuana</subject><subject>Municipal wastewater</subject><subject>Other wastewaters</subject><subject>Pollution</subject><subject>Pollution abatement</subject><subject>Street Drugs - analysis</subject><subject>Substance-Related Disorders - epidemiology</subject><subject>Tandem Mass Spectrometry</subject><subject>Therapeutic opiates</subject><subject>Waste Disposal, Fluid</subject><subject>Waste water</subject><subject>Wastewaters</subject><subject>Water Pollutants, Chemical - analysis</subject><subject>Water Pollution, Chemical - statistics &amp; numerical data</subject><subject>Water treatment and pollution</subject><issn>0269-7491</issn><issn>1873-6424</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1uFDEQhS0EIpPADRDyBhEWPZT_-mcTCY0CRIrEBjZsLLddEzzqaQ-2O9HsuAM3zElwMwPsIla2q756Zb1HyAsGSwasfrtZ4ni7C8OSQymBXAKHR2TB2kZUteTyMVkAr7uqkR07IacpbQBACiGekhMOikGpL8juahi89Zm6ON0k6kd6Z1LGO5Mx0rCm-RvS0t7P96_mJmJPz1cxmOzNG3r_4ye9TNlvyzOMMzKrUNNPCWcpQ3M0Y_K_uzZMY477Z-TJ2gwJnx_PM_Ll_eXn1cfq-tOHq9W768oqznNljatNz5xE11rF0PXcKmOMcB0IZ2UteCearhctKNnyulVWWC7RIErrHBNn5PVBdxfD9wlT1lufLA6DGTFMSTeqE9Bx9R-kEF0LTTOT5w-SrCkU8FZ2BZUH1MaQUsS13sXiU9xrBnrOT2_0IT8956dB6pJfGXt53DD1W3R_h_4EVoBXR8Aka4Z18df69I8TwKWCef_FgcPi8a3HqJP1OFp0PqLN2gX_8E9-AfNou6o</recordid><startdate>20100801</startdate><enddate>20100801</enddate><creator>Terzic, Senka</creator><creator>Senta, Ivan</creator><creator>Ahel, Marijan</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SU</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>KR7</scope><scope>7X8</scope><scope>7ST</scope><scope>7TV</scope><scope>7U7</scope><scope>SOI</scope></search><sort><creationdate>20100801</creationdate><title>Illicit drugs in wastewater of the city of Zagreb (Croatia) – Estimation of drug abuse in a transition country</title><author>Terzic, Senka ; Senta, Ivan ; Ahel, Marijan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c522t-cad6ab1d4ed8c51edb2c5aaa3d903dc46329379b3805482685c3c24eaee4cdd13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Amphetamines - analysis</topic><topic>Applied sciences</topic><topic>Cannabinoids - analysis</topic><topic>Chromatography, Liquid</topic><topic>Cities</topic><topic>Cocaine - analysis</topic><topic>Croatia</topic><topic>Drug abuse</topic><topic>Drug consumption</topic><topic>Drugs</topic><topic>Environmental Monitoring</topic><topic>Epidemiological Monitoring</topic><topic>Exact sciences and technology</topic><topic>Excretion</topic><topic>Heroin - analysis</topic><topic>Illicit</topic><topic>Illicit drugs</topic><topic>Inhabitants</topic><topic>LC–MS–MS</topic><topic>Marijuana</topic><topic>Municipal wastewater</topic><topic>Other wastewaters</topic><topic>Pollution</topic><topic>Pollution abatement</topic><topic>Street Drugs - analysis</topic><topic>Substance-Related Disorders - epidemiology</topic><topic>Tandem Mass Spectrometry</topic><topic>Therapeutic opiates</topic><topic>Waste Disposal, Fluid</topic><topic>Waste water</topic><topic>Wastewaters</topic><topic>Water Pollutants, Chemical - analysis</topic><topic>Water Pollution, Chemical - statistics &amp; numerical data</topic><topic>Water treatment and pollution</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Terzic, Senka</creatorcontrib><creatorcontrib>Senta, Ivan</creatorcontrib><creatorcontrib>Ahel, Marijan</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Environmental Engineering Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Civil Engineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Environment Abstracts</collection><collection>Pollution Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environment Abstracts</collection><jtitle>Environmental pollution (1987)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Terzic, Senka</au><au>Senta, Ivan</au><au>Ahel, Marijan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Illicit drugs in wastewater of the city of Zagreb (Croatia) – Estimation of drug abuse in a transition country</atitle><jtitle>Environmental pollution (1987)</jtitle><addtitle>Environ Pollut</addtitle><date>2010-08-01</date><risdate>2010</risdate><volume>158</volume><issue>8</issue><spage>2686</spage><epage>2693</epage><pages>2686-2693</pages><issn>0269-7491</issn><eissn>1873-6424</eissn><coden>ENVPAF</coden><abstract>A comprehensive study of various psychoactive substances and their metabolites was performed in the wastewater treatment plant of the city of Zagreb (780 000 inhabitants) using liquid chromatography/tandem mass spectrometry (LC–MS–MS). The estimation of drug abuse for five different illicit drugs, including heroin, cocaine, marijuana, amphetamine and ecstasy, was made on the basis of their representative excretion rates, which were determined over a period of 8 months. Marijuana (1000 kg/year), heroin (75 kg/year) and cocaine (47 kg/year) were found to be the most frequently consumed illicit drugs, while the consumption of amphetamine-type drugs was much lower (1–3 kg/year). A comparison with other reports indicated that drug abuse profiles in transition countries might be different from those reported for Western Europe, in particular with respect to the comparatively increased consumption of heroin. Enhanced consumption of stimulating drugs (cocaine and ectasy) was systematically detected during weekends. Wastewater analysis is a promising complementary tool to assess drug abuse patterns.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>20510491</pmid><doi>10.1016/j.envpol.2010.04.020</doi><tpages>8</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0269-7491
ispartof Environmental pollution (1987), 2010-08, Vol.158 (8), p.2686-2693
issn 0269-7491
1873-6424
language eng
recordid cdi_proquest_miscellaneous_759309251
source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Amphetamines - analysis
Applied sciences
Cannabinoids - analysis
Chromatography, Liquid
Cities
Cocaine - analysis
Croatia
Drug abuse
Drug consumption
Drugs
Environmental Monitoring
Epidemiological Monitoring
Exact sciences and technology
Excretion
Heroin - analysis
Illicit
Illicit drugs
Inhabitants
LC–MS–MS
Marijuana
Municipal wastewater
Other wastewaters
Pollution
Pollution abatement
Street Drugs - analysis
Substance-Related Disorders - epidemiology
Tandem Mass Spectrometry
Therapeutic opiates
Waste Disposal, Fluid
Waste water
Wastewaters
Water Pollutants, Chemical - analysis
Water Pollution, Chemical - statistics & numerical data
Water treatment and pollution
title Illicit drugs in wastewater of the city of Zagreb (Croatia) – Estimation of drug abuse in a transition country
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-14T01%3A01%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Illicit%20drugs%20in%20wastewater%20of%20the%20city%20of%20Zagreb%20(Croatia)%20%E2%80%93%20Estimation%20of%20drug%20abuse%20in%20a%20transition%20country&rft.jtitle=Environmental%20pollution%20(1987)&rft.au=Terzic,%20Senka&rft.date=2010-08-01&rft.volume=158&rft.issue=8&rft.spage=2686&rft.epage=2693&rft.pages=2686-2693&rft.issn=0269-7491&rft.eissn=1873-6424&rft.coden=ENVPAF&rft_id=info:doi/10.1016/j.envpol.2010.04.020&rft_dat=%3Cproquest_cross%3E759309251%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1777102849&rft_id=info:pmid/20510491&rft_els_id=S0269749110001727&rfr_iscdi=true