Mapping the cleavage site in protein synthesis initiation factor eIF-4 gamma of the 2A proteases from human Coxsackievirus and rhinovirus

The rate-limiting step of eukaryotic protein synthesis is the binding of mRNA to the 40 S ribosomal subunit, a step which is catalyzed by initiation factors of the eIF-4 (eukaryotic initiation factor 4) group: eIF-4A, eIF-4B, eIF-4E, and eIF-4 gamma. Infection of cells with picornaviruses of the rhi...

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Veröffentlicht in:	The Journal of biological chemistry 1993-09, Vol.268 (26), p.19200-19203
Hauptverfasser:	LAMPHEAR, B. J, RIQIANG YAN, FANG YANG, WATERS, D, LIEBIG, H.-D, KLUMP, H, KUECHLER, E, SKERN, T, RHOADS, R. E
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Binding Sites Biological and medical sciences Cysteine Endopeptidases - metabolism Enterovirus - metabolism Fundamental and applied biological sciences. Psychology Humans Molecular and cellular biology Molecular genetics Molecular Sequence Data Peptide Chain Initiation, Translational Peptide Fragments - chemistry Peptide Fragments - isolation & purification Peptide Initiation Factors - metabolism Protein Biosynthesis Rabbits Reticulocytes - metabolism Rhinovirus - metabolism RNA, Messenger - metabolism RNA, Viral - metabolism Translation. Translation factors. Protein processing Viral Proteins
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