Expression of insulin-like growth factor binding proteins in human breast cancer correlates with estrogen receptor status

The insulin‐like growth factors (IGFs) have been implicated in the growth regulation of human breast cancer. Since the IGFs are associated with specific binding proteins (IGFBPs) which may modulate receptor/ligand interactions, production of IGFBPs by breast cancer cells could alter their IGF‐depend...

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Veröffentlicht in:	Journal of cellular biochemistry 1993-06, Vol.52 (2), p.196-205
Hauptverfasser:	Figueroa, Jose A., Jackson, James G., McGuire, William L., Krywicki, Robert F., Yee, Douglas
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blotting, Western breast cancer cell lines Breast Neoplasms - metabolism Carrier Proteins - biosynthesis Carrier Proteins - genetics Carrier Proteins - metabolism cell growth Gynecology. Andrology. Obstetrics hormonal regulation Humans IGFs Immunoblotting Insulin-Like Growth Factor Binding Proteins Mammary gland diseases Medical sciences Receptors, Estrogen - metabolism RNA, Messenger - biosynthesis Somatomedins - metabolism tumor biology Tumor Cells, Cultured Tumors
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