Magnitude and implications of spontaneous hemodynamic variability in primary pulmonary hypertension

The pulmonary artery (PA) pressure and pulmonary resistance at rest have been noted to vary spontaneously in patients with primary pulmonary hypertension. To evaluate this variation, in 12 patients (8 women, 4 men, aged 43 ± 13 years), hourly measurements were made for 6 consecutive hours of heart r...

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