More on the Survival and Ventricular Enlargement Trial
To the Editor: In describing the results of a placebo-controlled study of captopril in patients with left ventricular dysfunction after myocardial infarction, Pfeffer et al. (Sept. 3, 1992, issue) 1 reported that significantly fewer patients given captopril had at least one recurrent infarction (170...
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| Veröffentlicht in: | The New England journal of medicine 1993-10, Vol.329 (16), p.1204-1206 |
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| container_issue | 16 |
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| container_title | The New England journal of medicine |
| container_volume | 329 |
| creator | Ganley, Charles J Hung, H.M. James Temple, Robert Pfeffer, Marc A Moye, Lemuel A Rutherford, John Braunwald, Eugene |
| description | To the Editor:
In describing the results of a placebo-controlled study of captopril in patients with left ventricular dysfunction after myocardial infarction, Pfeffer et al. (Sept. 3, 1992, issue)
1
reported that significantly fewer patients given captopril had at least one recurrent infarction (170 patients in the placebo group and 133 in the captopril group). This result is not as clear-cut as the report suggests. The favorable finding arose from a post hoc reanalysis of the data.
The protocol of the Survival and Ventricular Enlargement (SAVE) trial precisely defined the criteria for recurrent myocardial infarction: 1) new Q or QS waves . . . |
| doi_str_mv | 10.1056/NEJM199310143291616 |
| format | Article |
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In describing the results of a placebo-controlled study of captopril in patients with left ventricular dysfunction after myocardial infarction, Pfeffer et al. (Sept. 3, 1992, issue)
1
reported that significantly fewer patients given captopril had at least one recurrent infarction (170 patients in the placebo group and 133 in the captopril group). This result is not as clear-cut as the report suggests. The favorable finding arose from a post hoc reanalysis of the data.
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In describing the results of a placebo-controlled study of captopril in patients with left ventricular dysfunction after myocardial infarction, Pfeffer et al. (Sept. 3, 1992, issue)
1
reported that significantly fewer patients given captopril had at least one recurrent infarction (170 patients in the placebo group and 133 in the captopril group). This result is not as clear-cut as the report suggests. The favorable finding arose from a post hoc reanalysis of the data.
The protocol of the Survival and Ventricular Enlargement (SAVE) trial precisely defined the criteria for recurrent myocardial infarction: 1) new Q or QS waves . . .</description><subject>Captopril - therapeutic use</subject><subject>Electrocardiography</subject><subject>Humans</subject><subject>Hypertrophy, Left Ventricular - drug therapy</subject><subject>Hypertrophy, Left Ventricular - physiopathology</subject><subject>Myocardial Infarction - physiopathology</subject><subject>Recurrence</subject><subject>Ventricular Function, Left</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UMlOwzAQtRColMIXIKScuKCAnXG8HFHVsqiFA4Wr5TgOpIqTYieV-HuMWnFCzGFGM28Z6SF0TvA1wTm7eZo9LomUQDChkEnCCDtAY5IDpJRidojGGGcipVzCMToJYY1jESpHaCSAcy7lGLFl523StUn_YZOXwW_rrW4S3ZbJm217X5uh0T6ZtbG_WxdPycrXujlFR5Vugj3bzwl6nc9W0_t08Xz3ML1dpCY-6NOMgTEGa4kFSCNyyDllUMS1AG51pTMtCiLKvGQSRGGgKrKKcUtYRQSlFUzQ5c5347vPwYZeuToY2zS6td0QFM9lRmUuIhF2ROO7ELyt1MbXTvsvRbD6SUv9kVZUXezth8LZ8lezjyfiVzvcuaBau3b_un0DbmNv-g</recordid><startdate>19931014</startdate><enddate>19931014</enddate><creator>Ganley, Charles J</creator><creator>Hung, H.M. James</creator><creator>Temple, Robert</creator><creator>Pfeffer, Marc A</creator><creator>Moye, Lemuel A</creator><creator>Rutherford, John</creator><creator>Braunwald, Eugene</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19931014</creationdate><title>More on the Survival and Ventricular Enlargement Trial</title><author>Ganley, Charles J ; Hung, H.M. James ; Temple, Robert ; Pfeffer, Marc A ; Moye, Lemuel A ; Rutherford, John ; Braunwald, Eugene</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c377t-263ccc0a90839c85357463b908b37eafa2a8b18d5d6938bc3fb2f67e16f1844f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Captopril - therapeutic use</topic><topic>Electrocardiography</topic><topic>Humans</topic><topic>Hypertrophy, Left Ventricular - drug therapy</topic><topic>Hypertrophy, Left Ventricular - physiopathology</topic><topic>Myocardial Infarction - physiopathology</topic><topic>Recurrence</topic><topic>Ventricular Function, Left</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ganley, Charles J</creatorcontrib><creatorcontrib>Hung, H.M. James</creatorcontrib><creatorcontrib>Temple, Robert</creatorcontrib><creatorcontrib>Pfeffer, Marc A</creatorcontrib><creatorcontrib>Moye, Lemuel A</creatorcontrib><creatorcontrib>Rutherford, John</creatorcontrib><creatorcontrib>Braunwald, Eugene</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ganley, Charles J</au><au>Hung, H.M. James</au><au>Temple, Robert</au><au>Pfeffer, Marc A</au><au>Moye, Lemuel A</au><au>Rutherford, John</au><au>Braunwald, Eugene</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>More on the Survival and Ventricular Enlargement Trial</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>1993-10-14</date><risdate>1993</risdate><volume>329</volume><issue>16</issue><spage>1204</spage><epage>1206</epage><pages>1204-1206</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>To the Editor:
In describing the results of a placebo-controlled study of captopril in patients with left ventricular dysfunction after myocardial infarction, Pfeffer et al. (Sept. 3, 1992, issue)
1
reported that significantly fewer patients given captopril had at least one recurrent infarction (170 patients in the placebo group and 133 in the captopril group). This result is not as clear-cut as the report suggests. The favorable finding arose from a post hoc reanalysis of the data.
The protocol of the Survival and Ventricular Enlargement (SAVE) trial precisely defined the criteria for recurrent myocardial infarction: 1) new Q or QS waves . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>8377799</pmid><doi>10.1056/NEJM199310143291616</doi><tpages>3</tpages></addata></record> |
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| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 1993-10, Vol.329 (16), p.1204-1206 |
| issn | 0028-4793 1533-4406 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75924958 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; ProQuest Central UK/Ireland; New England Journal of Medicine |
| subjects | Captopril - therapeutic use Electrocardiography Humans Hypertrophy, Left Ventricular - drug therapy Hypertrophy, Left Ventricular - physiopathology Myocardial Infarction - physiopathology Recurrence Ventricular Function, Left |
| title | More on the Survival and Ventricular Enlargement Trial |
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