Tn, a carcinoma‐associated antigen, reacts with anti‐Tn of normal human sera

Tn antigen is the immediate precursor of the carcinoma (CA)‐associated T antigen; both are masked in non‐CA tissues. Tn antigen was detected by absorption of human anti‐Tn antibody in 46 of 50 primary breast CAs and in all 6 metastases originating from Tn‐positive primary CAs. Thirteen of 25 (52%) a...

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Veröffentlicht in:	Cancer 1985-02, Vol.55 (3), p.561-569
Hauptverfasser:	Springer, Georg F., Taylor, Clive R., Howard, Donald R., Tegtmeyer, Herta, Desai, Parimal R., Murthy, Satya M., Felder, Barbara, Scanlon, Edward F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Antigen-Antibody Reactions Antigens, Neoplasm - immunology Antigens, Tumor-Associated, Carbohydrate Antigens, Viral, Tumor - immunology Biological and medical sciences Blood Group Antigens - immunology Breast Neoplasms - immunology Carcinoma - immunology Carcinoma, Intraductal, Noninfiltrating - immunology Cell Line Female Hemagglutination Tests Histocytochemistry Host-tumor relations. Immunology. Biological markers Humans Immunochemistry Immunosorbent Techniques Lymphoma - immunology Mammary Neoplasms, Experimental - immunology Medical sciences Mice Neoplasm Metastasis Neoplasm Recurrence, Local Rats Tumors
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