TETRAFIBRICIN, A NOVEL FIBRINOGEN RECEPTOR ANTAGONIST: I. TAXONOMY, FERMENTATION, ISOLATION, CHARACTERIZATION AND BIOLOGICAL ACTIVITIES

Tetrafibricin is a novel fibrinogen receptor antagonist produced by Streptomyces neyagawaensis NR0577. It was isolated from the culture broth by Diaion HP-21 adsorption, MeOH extraction, MCI GEL CHP-20P column chromatography, preparative HPLC and Toyopearl HW-40 SF column chromatography. The physico...

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Veröffentlicht in:	Journal of antibiotics 1993/07/25, Vol.46(7), pp.1039-1046
Hauptverfasser:	KAMIYAMA, TSUTOMU, UMINO, TAKAYUKI, FUJISAKI, NORIKO, FUJIMORI, KUMIKO, SATOH, TOMOKO, YAMASHITA, YUKO, OHSHIMA, SHOICHI, WATANABE, JUNKO, YOKOSE, KAZUTERU
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents Applied microbiology Biological and medical sciences Chemical Phenomena Chemistry, Physical Chemotherapic agents Fermentation Fundamental and applied biological sciences. Psychology Humans In Vitro Techniques Macrolides Microbiology Platelet Membrane Glycoproteins - antagonists & inhibitors Streptomyces - classification Streptomyces - metabolism
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