Association of a TGF-β1 gene −509 C/T polymorphism with breast cancer risk: a meta-analysis

Transforming growth factor-β1 (TGF-β1) is negative regulator of cell proliferation and the cell cycle, and plasma levels of TGF-β1 are twice as high in TGF-β1 −509 T homozygotes as in −509 C homozygotes. Published studies on the association between the TGF-β1 gene −509 C/T polymorphism and breast ca...

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Veröffentlicht in:	Breast cancer research and treatment 2010-11, Vol.124 (2), p.481-485
Hauptverfasser:	Woo, Sang Uk, Park, Kyong Hwa, Woo, Ok Hee, Yang, Dae Sik, Kim, Ae-Ree, Lee, Eun Sook, Lee, Jae-Bok, Kim, Yeul Hong, Kim, Jun Suk, Seo, Jae Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	509 C/T polymorphism Biological and medical sciences Bone morphogenetic proteins Breast cancer Breast cancer risk Breast Neoplasms - genetics Cancer Case-Control Studies Epidemiology Female Gene Frequency Genes Genetic aspects Genetic Predisposition to Disease Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Medicine Medicine & Public Health meta-analysis Odds Ratio Oncology Polymorphism, Single Nucleotide Risk Assessment Risk Factors TGF-β1 Transforming Growth Factor beta1 - genetics Transforming growth factors Tumors
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