Presence of CD4+ T suppressor cells in mice rendered unresponsive to tumor antigens by intravenous injection of irradiated tumor cells

We used in vivo and in vitro assays to determine whether suppressor cells are generated in mice rendered unresponsive to tumor‐specific antigens by intravenous (i.v.) injection of non‐replicating tumor cells. The results show that a single i.v. injection of 2 × 107 irradiated P815 tumor cells result...

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