Amphoterin, the 30-kDa protein in a family of HMG1-type polypeptides. Enhanced expression in transformed cells, leading edge localization, and interactions with plasminogen activation

Amphoterin is a heparin-binding protein that is developmentally regulated in brain and functionally involved in neurite outgrowth. Unexpectedly, amphoterin has a high mobility group 1 (HMG1)-type sequence. In the present study we have expressed amphoterin cDNA in a baculovirus vector and produced an...

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Veröffentlicht in:	The Journal of biological chemistry 1993-09, Vol.268 (26), p.19726-19738
Hauptverfasser:	PARKKINEN, J, RAULO, E, MERENMIES, J, NOLO, R, KAJANDER, E. O, BAUMANN, M, RAUVALA, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical, structural and metabolic biochemistry Animals Baculoviridae - genetics Base Sequence Binding and carrier proteins Biological and medical sciences Brain - metabolism Carrier Proteins - biosynthesis Carrier Proteins - isolation & purification Carrier Proteins - metabolism Cell Line Cell Line, Transformed Electrophoresis, Polyacrylamide Gel Fundamental and applied biological sciences. Psychology Gene Expression Genetic Vectors High Mobility Group Proteins - biosynthesis High Mobility Group Proteins - metabolism HMGB1 Protein Humans Kinetics Microscopy, Fluorescence Microscopy, Immunoelectron Molecular Sequence Data Molecular Weight Moths Nerve Tissue Proteins - biosynthesis Oligodeoxyribonucleotides Peptide Fragments - chemistry Peptide Fragments - isolation & purification Plasminogen - metabolism Proteins Recombinant Proteins - biosynthesis Recombinant Proteins - isolation & purification Recombinant Proteins - metabolism Sequence Homology, Amino Acid Transfection
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