Paradoxical Changes in Iodine-131 Scintigraphic Findings in Advanced Follicular Thyroid Cancer
We present the findings on iodine-131 (131I) scintigraphy, thallium-201 (201Tl) scintigraphy and quantitative thyroglobulin (QTG) estimation in two patients with follicular carcinoma of the thyroid with extensive metastases. The lesions were initially seen on 131I scintigraphs, but were not subseque...
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| Veröffentlicht in: | The Journal of nuclear medicine (1978) 1993-09, Vol.34 (9), p.1574-1576 |
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| container_end_page | 1576 |
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| container_issue | 9 |
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| container_title | The Journal of nuclear medicine (1978) |
| container_volume | 34 |
| creator | Krishna, Lalitha Dadparvar, Simin Brady, Luther W Micaily, Bizhan Meihofer, Mary Slizofski, Walter J Brown, Steven J Chevres, Anita Roman, Regina Khan, Angabeen S |
| description | We present the findings on iodine-131 (131I) scintigraphy, thallium-201 (201Tl) scintigraphy and quantitative thyroglobulin (QTG) estimation in two patients with follicular carcinoma of the thyroid with extensive metastases. The lesions were initially seen on 131I scintigraphs, but were not subsequently visualized with scanning doses of 131I (5 mCi), while retaining their ability to produce increasing amounts of thyroglobulin and take up 201Tl. Implications in choosing the appropriate diagnostic tests in the management of differentiated thyroid cancer are discussed. |
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The lesions were initially seen on 131I scintigraphs, but were not subsequently visualized with scanning doses of 131I (5 mCi), while retaining their ability to produce increasing amounts of thyroglobulin and take up 201Tl. Implications in choosing the appropriate diagnostic tests in the management of differentiated thyroid cancer are discussed.</description><identifier>ISSN: 0161-5505</identifier><identifier>EISSN: 1535-5667</identifier><identifier>PMID: 8355078</identifier><language>eng</language><publisher>United States: Soc Nuclear Med</publisher><subject>Adenocarcinoma - diagnostic imaging ; Adenocarcinoma - secondary ; Adenocarcinoma - therapy ; Adult ; Aged ; Combined Modality Therapy ; Humans ; Iodine Radioisotopes ; Male ; Radionuclide Imaging ; Thallium Radioisotopes ; Thyroglobulin - blood ; Thyroid Neoplasms - diagnostic imaging ; Thyroid Neoplasms - therapy ; Time Factors</subject><ispartof>The Journal of nuclear medicine (1978), 1993-09, Vol.34 (9), p.1574-1576</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8355078$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Krishna, Lalitha</creatorcontrib><creatorcontrib>Dadparvar, Simin</creatorcontrib><creatorcontrib>Brady, Luther W</creatorcontrib><creatorcontrib>Micaily, Bizhan</creatorcontrib><creatorcontrib>Meihofer, Mary</creatorcontrib><creatorcontrib>Slizofski, Walter J</creatorcontrib><creatorcontrib>Brown, Steven J</creatorcontrib><creatorcontrib>Chevres, Anita</creatorcontrib><creatorcontrib>Roman, Regina</creatorcontrib><creatorcontrib>Khan, Angabeen S</creatorcontrib><title>Paradoxical Changes in Iodine-131 Scintigraphic Findings in Advanced Follicular Thyroid Cancer</title><title>The Journal of nuclear medicine (1978)</title><addtitle>J Nucl Med</addtitle><description>We present the findings on iodine-131 (131I) scintigraphy, thallium-201 (201Tl) scintigraphy and quantitative thyroglobulin (QTG) estimation in two patients with follicular carcinoma of the thyroid with extensive metastases. The lesions were initially seen on 131I scintigraphs, but were not subsequently visualized with scanning doses of 131I (5 mCi), while retaining their ability to produce increasing amounts of thyroglobulin and take up 201Tl. Implications in choosing the appropriate diagnostic tests in the management of differentiated thyroid cancer are discussed.</description><subject>Adenocarcinoma - diagnostic imaging</subject><subject>Adenocarcinoma - secondary</subject><subject>Adenocarcinoma - therapy</subject><subject>Adult</subject><subject>Aged</subject><subject>Combined Modality Therapy</subject><subject>Humans</subject><subject>Iodine Radioisotopes</subject><subject>Male</subject><subject>Radionuclide Imaging</subject><subject>Thallium Radioisotopes</subject><subject>Thyroglobulin - blood</subject><subject>Thyroid Neoplasms - diagnostic imaging</subject><subject>Thyroid Neoplasms - therapy</subject><subject>Time Factors</subject><issn>0161-5505</issn><issn>1535-5667</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotkF1LwzAUhoMoc05_gpArvSo0y1dzOYrTwUDBeWvJZ5uRpjNd1f17O7erczjPw8vLuQBTRDHNKGP8EkxzxFBGaU6vwU3fb_M8Z0VRTMCkwOOVF1Pw-SaTNN2v1zLAspGxtj30Ea4646PNEEbwXfu493WSu8ZruPRxJPW_tDDfMmpr4LILweshyAQ3zSF13sDySNItuHIy9PbuPGfgY_m0KV-y9evzqlyss2asu8-4dtIpTQtCqSIEaYEVVdqNO8st05YZLOy84FIIbYTimDvmNEFyrqjjGM_Awyl3l7qvwfb7qvW9tiHIaLuhrzgV-VwQNor3Z3FQrTXVLvlWpkN1fsjIH0-88XXz45Ot4qCDlekob2OLSSUqRDnBfzD5a4s</recordid><startdate>199309</startdate><enddate>199309</enddate><creator>Krishna, Lalitha</creator><creator>Dadparvar, Simin</creator><creator>Brady, Luther W</creator><creator>Micaily, Bizhan</creator><creator>Meihofer, Mary</creator><creator>Slizofski, Walter J</creator><creator>Brown, Steven J</creator><creator>Chevres, Anita</creator><creator>Roman, Regina</creator><creator>Khan, Angabeen S</creator><general>Soc Nuclear Med</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>199309</creationdate><title>Paradoxical Changes in Iodine-131 Scintigraphic Findings in Advanced Follicular Thyroid Cancer</title><author>Krishna, Lalitha ; Dadparvar, Simin ; Brady, Luther W ; Micaily, Bizhan ; Meihofer, Mary ; Slizofski, Walter J ; Brown, Steven J ; Chevres, Anita ; Roman, Regina ; Khan, Angabeen S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h153t-7cfafbc58455b441c93b5bcfb4460e6ce6d39e287a99cd9b737f6fc41a2b5f733</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Adenocarcinoma - diagnostic imaging</topic><topic>Adenocarcinoma - secondary</topic><topic>Adenocarcinoma - therapy</topic><topic>Adult</topic><topic>Aged</topic><topic>Combined Modality Therapy</topic><topic>Humans</topic><topic>Iodine Radioisotopes</topic><topic>Male</topic><topic>Radionuclide Imaging</topic><topic>Thallium Radioisotopes</topic><topic>Thyroglobulin - blood</topic><topic>Thyroid Neoplasms - diagnostic imaging</topic><topic>Thyroid Neoplasms - therapy</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Krishna, Lalitha</creatorcontrib><creatorcontrib>Dadparvar, Simin</creatorcontrib><creatorcontrib>Brady, Luther W</creatorcontrib><creatorcontrib>Micaily, Bizhan</creatorcontrib><creatorcontrib>Meihofer, Mary</creatorcontrib><creatorcontrib>Slizofski, Walter J</creatorcontrib><creatorcontrib>Brown, Steven J</creatorcontrib><creatorcontrib>Chevres, Anita</creatorcontrib><creatorcontrib>Roman, Regina</creatorcontrib><creatorcontrib>Khan, Angabeen S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of nuclear medicine (1978)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Krishna, Lalitha</au><au>Dadparvar, Simin</au><au>Brady, Luther W</au><au>Micaily, Bizhan</au><au>Meihofer, Mary</au><au>Slizofski, Walter J</au><au>Brown, Steven J</au><au>Chevres, Anita</au><au>Roman, Regina</au><au>Khan, Angabeen S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Paradoxical Changes in Iodine-131 Scintigraphic Findings in Advanced Follicular Thyroid Cancer</atitle><jtitle>The Journal of nuclear medicine (1978)</jtitle><addtitle>J Nucl Med</addtitle><date>1993-09</date><risdate>1993</risdate><volume>34</volume><issue>9</issue><spage>1574</spage><epage>1576</epage><pages>1574-1576</pages><issn>0161-5505</issn><eissn>1535-5667</eissn><abstract>We present the findings on iodine-131 (131I) scintigraphy, thallium-201 (201Tl) scintigraphy and quantitative thyroglobulin (QTG) estimation in two patients with follicular carcinoma of the thyroid with extensive metastases. 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| ispartof | The Journal of nuclear medicine (1978), 1993-09, Vol.34 (9), p.1574-1576 |
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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adenocarcinoma - diagnostic imaging Adenocarcinoma - secondary Adenocarcinoma - therapy Adult Aged Combined Modality Therapy Humans Iodine Radioisotopes Male Radionuclide Imaging Thallium Radioisotopes Thyroglobulin - blood Thyroid Neoplasms - diagnostic imaging Thyroid Neoplasms - therapy Time Factors |
| title | Paradoxical Changes in Iodine-131 Scintigraphic Findings in Advanced Follicular Thyroid Cancer |
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