The solution conformation Ac-Pen-Arg-Gly-Asp-Cys-OH, a potent fibrinogen receptor antagonist

The solution conformation of , a potent fibrinogen receptor antagonist, was characterized in DMSO‐d6 by the combination of nmr and molecular modeling. The conformational space available to the peptide was explored using a distance geometry algorithm with distance constraints derived from 1H‐nmr spec...

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Veröffentlicht in:	Biopolymers 1993-08, Vol.33 (8), p.1287-1297
Hauptverfasser:	Bogusky, Michael J., Naylor, Adel M., Mertzman, Michael E., Pitzenberger, Steven M., Nutt, Ruth F., Brady, Stephen F., Colton, Christiane D., Veber, Daniel F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical, structural and metabolic biochemistry Biological and medical sciences Fundamental and applied biological sciences. Psychology General aspects, investigation methods Molecular Sequence Data Peptides, Cyclic - chemistry Platelet Membrane Glycoproteins - antagonists & inhibitors Protein Conformation Proteins Solutions
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