Enhancement of Antimicrobial Defense Activities of Immunoglobulins in Lung

We studied the effect of immunoglobulins (monomeric IgG, monomeric IgA, secretoryIgA) and bronchoalveolar lavage on the bactericidal activity by neutrophils. Results are as follows 1. Escherichia coli (E.coli) was killed by secretory IgA, and E. coli was more killed by secretory IgA with neutrophils...

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Veröffentlicht in:	Kansenshogaku Zasshi 1984/11/20, Vol.58(11), pp.1139-1143
Hauptverfasser:	KAMEOKA, Yoko, NAKAGAWA, Masaru, TAMURA, Masakazu, YASUOKA, Isao, TSUBURA, Eiro
Format:	Artikel
Sprache:	eng ; jpn
Schlagworte:	bactericidal activity bronchoalveolar lavage Escherichia coli - immunology Humans immunoglobulin Immunoglobulin A, Secretory - immunology Immunoglobulin G - immunology In Vitro Techniques Lung - immunology neutrophil Neutrophils - immunology Pulmonary Alveoli - immunology Therapeutic Irrigation
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Beschreibung
Zusammenfassung:	We studied the effect of immunoglobulins (monomeric IgG, monomeric IgA, secretoryIgA) and bronchoalveolar lavage on the bactericidal activity by neutrophils. Results are as follows 1. Escherichia coli (E.coli) was killed by secretory IgA, and E. coli was more killed by secretory IgA with neutrophils. 2. Bronchoalveolar lavage enhanced the bactericidal activity by neutrophils less than fresh plasma. 3. Secretory IgA or monomeric IgA enhanced the bactericidal activity by neutrophils with bronchoalveolar levage.
ISSN:	0387-5911 1884-569X
DOI:	10.11150/kansenshogakuzasshi1970.58.1139