Mechanism of CRP-cAMP activation of lac operon transcription initiation activation of the P1 promoter

CRP-cAMP was shown to activate transcription initiation at the Escherichia coli lac promoter in vitro as a result of two separate effects. An indirect component of the activation resulted from an enhancement of the fraction of promoters productively bound by RNA polymerase. This effect was due large...

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Veröffentlicht in:	Journal of molecular biology 1984-12, Vol.180 (4), p.881-909
Hauptverfasser:	Malan, T.Philip, Kolb, Annie, Buc, Henri, McClure, William R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Applied sciences Cyclic AMP DNA, Superhelical DNA-Directed RNA Polymerases - metabolism Escherichia coli - genetics Exact sciences and technology Kinetics Lac Operon Models, Genetic Other techniques and industries Receptors, Cyclic AMP Templates, Genetic Transcription, Genetic
Online-Zugang:	Volltext
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