Advances in prognostic factors in acute pancreatitis:a mini-review

BACKGROUND:Early assessment of the severity of acute pancreatitis is essential to the proper management of the disease.It is dependent on the criteria of the Atlanta classification system.DATA SOURCES:PubMed search of recent relevant articles was performed to identify information about the severity...

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Veröffentlicht in:Hepatobiliary & pancreatic diseases international 2010-10, Vol.9 (5), p.482-486
Hauptverfasser: Pavlidis, Theodoros E, Pavlidis, Efstathios T, Sakantamis, Athanasios K
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container_issue 5
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container_title Hepatobiliary & pancreatic diseases international
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creator Pavlidis, Theodoros E
Pavlidis, Efstathios T
Sakantamis, Athanasios K
description BACKGROUND:Early assessment of the severity of acute pancreatitis is essential to the proper management of the disease.It is dependent on the criteria of the Atlanta classification system.DATA SOURCES:PubMed search of recent relevant articles was performed to identify information about the severity and prognosis of acute pancreatitis.RESULTS:The scoring systems included the Ranson’s or Glasgow’s criteria ≥3,the APACHE II classification system ≥8,and the Balthazar’s criteria ≥4 according to the computed tomography enhanced scanning findings.The single factors on admission included age >65 years,obesity,hemoconcentration(>44%),abnormal chest X-ray,creatinine >2 mg/dl,C-reactive protein>150 mg/dl,procalcitonin >1.8 ng/ml,albumin <2.5 mg/dl,calcium <8.5 mg/dl,early hyperglycemia,increased intra-abdominal pressure,macrophage migration inhibitory factor,or a combination of IL-10 >50 pg/ml with calcium <6.6 mg/dl.CONCLUSION:The prediction of the severity of acute pancreatitis is largely based on well defined multiple factor scoring systems as well as several single risk factors.
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subjects acute
Acute Disease
factor
Humans
infected
necrosis
pancreatitis
Pancreatitis - blood
Pancreatitis - diagnosis
prediction
Prognosis
prognostic
risk
Risk Factors
scoring
severity
Severity of Illness Index
sign
system
title Advances in prognostic factors in acute pancreatitis:a mini-review
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