Critical Examination of an Enzyme Immunoassay for Detection of Positive IgM Antibodies Against Toxoplasma in Newborns
The Toxonostika® IgM test, which has been examined in this study, is a modified antibody capture test (7). Evaluation with sera from newborns revealed that, like in the ELISA tested in 1988, doubtful or false positive results were obtained in 10% of the cases (6). Therefore, a positive toxoplasmosis...
Gespeichert in:
| Veröffentlicht in: | Zentralblatt für Bakteriologie 1993-06, Vol.278 (4), p.566-569 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 569 |
|---|---|
| container_issue | 4 |
| container_start_page | 566 |
| container_title | Zentralblatt für Bakteriologie |
| container_volume | 278 |
| creator | Dohr, Angelika Oehme, Albrecht |
| description | The Toxonostika® IgM test, which has been examined in this study, is a modified antibody capture test (7). Evaluation with sera from newborns revealed that, like in the ELISA tested in 1988, doubtful or false positive results were obtained in 10% of the cases (6). Therefore, a positive toxoplasmosis IgM result in newborn sera should always be retested with another test system.
Bei dem von uns geprüften Toxonostika® IgM Test handelt es sich urn einen modifizierten antibody capture test (7). Die Überprüfung mit Neugeborenenseren zeigte, daß ebenfalls, wie bei dem von uns 1988 getesteten ELISA, bei etwa 10% zweifelhafte bzw. falsch positive Ergebnisse auftraten (6). Daher sollte bei Neugeborenenseren ein positives Toxoplasmose-IgM- Ergebnis immer mit einem weiteren Testsystem überprüft werden. |
| doi_str_mv | 10.1016/S0934-8840(11)80828-5 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_75881352</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0934884011808285</els_id><sourcerecordid>75881352</sourcerecordid><originalsourceid>FETCH-LOGICAL-c337t-fa9fa8b2efda1c5ae05b4c435017d6507968e508da0fecb50339363f12f1f34c3</originalsourceid><addsrcrecordid>eNqFkMFu1DAQhn0AlVJ4hEo-IASHUDuOE-8JrZZtqVQKEuVsTZxxZZTYiycpXZ6-aXe7V04jzXz_zOhj7FSKT1LI-uynWKiqMKYSH6T8aIQpTaFfsOND-xV7TfRbCF2KujpiR0ZppcrmmE2rHMbgoOfrexhChDGkyJPnEPk6_tsOyC-HYYoJiGDLfcr8C47onrEfieb83UzdfuPLOIY2dQGJL28hRBr5TbpPmx5oAB4iv8a_bcqR3rCXHnrCt_t6wn6dr29WX4ur7xeXq-VV4ZRqxsLDwoNpS_QdSKcBhW4rVyktZNPVWjSL2qAWpgPh0bVaKLVQtfKy9NKryqkT9n63d5PTnwlptEMgh30PEdNEttHGSKXLGdQ70OVElNHbTQ4D5K2Vwj4qtk-K7aNLK6V9Umz1nDvdH5jaAbtDau93nr_bz4FmyT5DdIEOWGVqraWZsc87DGcZdwGzJRcwOuxCnl3bLoX_PPIAu1ObrQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>75881352</pqid></control><display><type>article</type><title>Critical Examination of an Enzyme Immunoassay for Detection of Positive IgM Antibodies Against Toxoplasma in Newborns</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Dohr, Angelika ; Oehme, Albrecht</creator><creatorcontrib>Dohr, Angelika ; Oehme, Albrecht</creatorcontrib><description>The Toxonostika® IgM test, which has been examined in this study, is a modified antibody capture test (7). Evaluation with sera from newborns revealed that, like in the ELISA tested in 1988, doubtful or false positive results were obtained in 10% of the cases (6). Therefore, a positive toxoplasmosis IgM result in newborn sera should always be retested with another test system.
Bei dem von uns geprüften Toxonostika® IgM Test handelt es sich urn einen modifizierten antibody capture test (7). Die Überprüfung mit Neugeborenenseren zeigte, daß ebenfalls, wie bei dem von uns 1988 getesteten ELISA, bei etwa 10% zweifelhafte bzw. falsch positive Ergebnisse auftraten (6). Daher sollte bei Neugeborenenseren ein positives Toxoplasmose-IgM- Ergebnis immer mit einem weiteren Testsystem überprüft werden.</description><identifier>ISSN: 0934-8840</identifier><identifier>DOI: 10.1016/S0934-8840(11)80828-5</identifier><identifier>PMID: 8353327</identifier><language>eng</language><publisher>Jena: Urban & Fischer</publisher><subject>Animals ; Antibodies, Protozoan - analysis ; Antibodies, Protozoan - immunology ; Biological and medical sciences ; Enzyme-Linked Immunosorbent Assay ; False Positive Reactions ; Human protozoal diseases ; Humans ; Immunoglobulin M - analysis ; Immunoglobulin M - immunology ; Infant, Newborn ; Infectious diseases ; Medical sciences ; Parasitic diseases ; Protozoal diseases ; Toxoplasma - immunology ; Toxoplasmosis ; Toxoplasmosis - diagnosis</subject><ispartof>Zentralblatt für Bakteriologie, 1993-06, Vol.278 (4), p.566-569</ispartof><rights>1993 Gustav Fischer Verlag, Stuttgart · New York</rights><rights>1993 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c337t-fa9fa8b2efda1c5ae05b4c435017d6507968e508da0fecb50339363f12f1f34c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4865518$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8353327$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dohr, Angelika</creatorcontrib><creatorcontrib>Oehme, Albrecht</creatorcontrib><title>Critical Examination of an Enzyme Immunoassay for Detection of Positive IgM Antibodies Against Toxoplasma in Newborns</title><title>Zentralblatt für Bakteriologie</title><addtitle>Zentralbl Bakteriol</addtitle><description>The Toxonostika® IgM test, which has been examined in this study, is a modified antibody capture test (7). Evaluation with sera from newborns revealed that, like in the ELISA tested in 1988, doubtful or false positive results were obtained in 10% of the cases (6). Therefore, a positive toxoplasmosis IgM result in newborn sera should always be retested with another test system.
Bei dem von uns geprüften Toxonostika® IgM Test handelt es sich urn einen modifizierten antibody capture test (7). Die Überprüfung mit Neugeborenenseren zeigte, daß ebenfalls, wie bei dem von uns 1988 getesteten ELISA, bei etwa 10% zweifelhafte bzw. falsch positive Ergebnisse auftraten (6). Daher sollte bei Neugeborenenseren ein positives Toxoplasmose-IgM- Ergebnis immer mit einem weiteren Testsystem überprüft werden.</description><subject>Animals</subject><subject>Antibodies, Protozoan - analysis</subject><subject>Antibodies, Protozoan - immunology</subject><subject>Biological and medical sciences</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>False Positive Reactions</subject><subject>Human protozoal diseases</subject><subject>Humans</subject><subject>Immunoglobulin M - analysis</subject><subject>Immunoglobulin M - immunology</subject><subject>Infant, Newborn</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Parasitic diseases</subject><subject>Protozoal diseases</subject><subject>Toxoplasma - immunology</subject><subject>Toxoplasmosis</subject><subject>Toxoplasmosis - diagnosis</subject><issn>0934-8840</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMFu1DAQhn0AlVJ4hEo-IASHUDuOE-8JrZZtqVQKEuVsTZxxZZTYiycpXZ6-aXe7V04jzXz_zOhj7FSKT1LI-uynWKiqMKYSH6T8aIQpTaFfsOND-xV7TfRbCF2KujpiR0ZppcrmmE2rHMbgoOfrexhChDGkyJPnEPk6_tsOyC-HYYoJiGDLfcr8C47onrEfieb83UzdfuPLOIY2dQGJL28hRBr5TbpPmx5oAB4iv8a_bcqR3rCXHnrCt_t6wn6dr29WX4ur7xeXq-VV4ZRqxsLDwoNpS_QdSKcBhW4rVyktZNPVWjSL2qAWpgPh0bVaKLVQtfKy9NKryqkT9n63d5PTnwlptEMgh30PEdNEttHGSKXLGdQ70OVElNHbTQ4D5K2Vwj4qtk-K7aNLK6V9Umz1nDvdH5jaAbtDau93nr_bz4FmyT5DdIEOWGVqraWZsc87DGcZdwGzJRcwOuxCnl3bLoX_PPIAu1ObrQ</recordid><startdate>19930601</startdate><enddate>19930601</enddate><creator>Dohr, Angelika</creator><creator>Oehme, Albrecht</creator><general>Urban & Fischer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19930601</creationdate><title>Critical Examination of an Enzyme Immunoassay for Detection of Positive IgM Antibodies Against Toxoplasma in Newborns</title><author>Dohr, Angelika ; Oehme, Albrecht</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c337t-fa9fa8b2efda1c5ae05b4c435017d6507968e508da0fecb50339363f12f1f34c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Animals</topic><topic>Antibodies, Protozoan - analysis</topic><topic>Antibodies, Protozoan - immunology</topic><topic>Biological and medical sciences</topic><topic>Enzyme-Linked Immunosorbent Assay</topic><topic>False Positive Reactions</topic><topic>Human protozoal diseases</topic><topic>Humans</topic><topic>Immunoglobulin M - analysis</topic><topic>Immunoglobulin M - immunology</topic><topic>Infant, Newborn</topic><topic>Infectious diseases</topic><topic>Medical sciences</topic><topic>Parasitic diseases</topic><topic>Protozoal diseases</topic><topic>Toxoplasma - immunology</topic><topic>Toxoplasmosis</topic><topic>Toxoplasmosis - diagnosis</topic><toplevel>online_resources</toplevel><creatorcontrib>Dohr, Angelika</creatorcontrib><creatorcontrib>Oehme, Albrecht</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Zentralblatt für Bakteriologie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dohr, Angelika</au><au>Oehme, Albrecht</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Critical Examination of an Enzyme Immunoassay for Detection of Positive IgM Antibodies Against Toxoplasma in Newborns</atitle><jtitle>Zentralblatt für Bakteriologie</jtitle><addtitle>Zentralbl Bakteriol</addtitle><date>1993-06-01</date><risdate>1993</risdate><volume>278</volume><issue>4</issue><spage>566</spage><epage>569</epage><pages>566-569</pages><issn>0934-8840</issn><abstract>The Toxonostika® IgM test, which has been examined in this study, is a modified antibody capture test (7). Evaluation with sera from newborns revealed that, like in the ELISA tested in 1988, doubtful or false positive results were obtained in 10% of the cases (6). Therefore, a positive toxoplasmosis IgM result in newborn sera should always be retested with another test system.
Bei dem von uns geprüften Toxonostika® IgM Test handelt es sich urn einen modifizierten antibody capture test (7). Die Überprüfung mit Neugeborenenseren zeigte, daß ebenfalls, wie bei dem von uns 1988 getesteten ELISA, bei etwa 10% zweifelhafte bzw. falsch positive Ergebnisse auftraten (6). Daher sollte bei Neugeborenenseren ein positives Toxoplasmose-IgM- Ergebnis immer mit einem weiteren Testsystem überprüft werden.</abstract><cop>Jena</cop><pub>Urban & Fischer</pub><pmid>8353327</pmid><doi>10.1016/S0934-8840(11)80828-5</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0934-8840 |
| ispartof | Zentralblatt für Bakteriologie, 1993-06, Vol.278 (4), p.566-569 |
| issn | 0934-8840 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75881352 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Antibodies, Protozoan - analysis Antibodies, Protozoan - immunology Biological and medical sciences Enzyme-Linked Immunosorbent Assay False Positive Reactions Human protozoal diseases Humans Immunoglobulin M - analysis Immunoglobulin M - immunology Infant, Newborn Infectious diseases Medical sciences Parasitic diseases Protozoal diseases Toxoplasma - immunology Toxoplasmosis Toxoplasmosis - diagnosis |
| title | Critical Examination of an Enzyme Immunoassay for Detection of Positive IgM Antibodies Against Toxoplasma in Newborns |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T00%3A51%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Critical%20Examination%20of%20an%20Enzyme%20Immunoassay%20for%20Detection%20of%20Positive%20IgM%20Antibodies%20Against%20Toxoplasma%20in%20Newborns&rft.jtitle=Zentralblatt%20f%C3%BCr%20Bakteriologie&rft.au=Dohr,%20Angelika&rft.date=1993-06-01&rft.volume=278&rft.issue=4&rft.spage=566&rft.epage=569&rft.pages=566-569&rft.issn=0934-8840&rft_id=info:doi/10.1016/S0934-8840(11)80828-5&rft_dat=%3Cproquest_cross%3E75881352%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=75881352&rft_id=info:pmid/8353327&rft_els_id=S0934884011808285&rfr_iscdi=true |