Molecular Cloning and Expression of Murine Thromboxane Synthase

The complementary DNA (cDNA) for murine thromboxane synthase (TS) was isolated from a lung cDNA library. The full-length cDNA (1,910 bp) encodes a 533 amino acid protein (Mr 58,220) sharing 78% identity with human TS. Sequence comparison indicated that one of the two N-glycosylation sites, eight of...

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Veröffentlicht in:	Biochemical and biophysical research communications 1993-07, Vol.194 (2), p.741-748
Hauptverfasser:	Zhang, L.Q., Chase, M.B., Shen, R.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical, structural and metabolic biochemistry Animals Base Sequence Biological and medical sciences Blotting, Northern Cell Line Cloning, Molecular DNA Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology Gene Expression Gene Library Humans Isomerases Kidney - enzymology Lung - enzymology Mice Mice, Inbred BALB C Molecular Sequence Data Open Reading Frames Polymerase Chain Reaction - methods Restriction Mapping RNA - genetics RNA - isolation & purification RNA, Messenger - metabolism Sequence Homology, Amino Acid Spleen - enzymology Thromboxane-A Synthase - biosynthesis Thromboxane-A Synthase - genetics Transfection
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