Dopamine receptors in the basal ganglia: Relevance to parkinson's disease

At least five receptors for dopamine (D1–D5) have been recognised from molecular biological studies, and their pharmacological properties and brain localisations have been determined. The D1 and D2 subtypes are the principal subtypes in brain, and their cellular localisations in the caudate nucleus...

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Veröffentlicht in:	Movement disorders 1993, Vol.8 (3), p.263-270
1. Verfasser:	Strange, Philip G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Basal Ganglia - drug effects Basal Ganglia - metabolism Basal Ganglia - physiopathology Basal Ganglia Diseases - drug therapy Basal Ganglia Diseases - physiopathology Biological and medical sciences Brain - drug effects Brain - metabolism Brain - physiopathology Clozapine - metabolism Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dopamine Agents - metabolism Dopamine Agents - pharmacokinetics Dopamine Agents - therapeutic use Dopamine D2 Receptor Antagonists Dopamine receptors Drug treatment Female Haloperidol - metabolism Humans Levodopa - therapeutic use Male Medical sciences Motor control Neostriatum Neostriatum - drug effects Neostriatum - metabolism Neural Pathways - metabolism Neural Pathways - physiopathology Neurology Parkinson Disease - drug therapy Parkinson Disease - metabolism Parkinson Disease - physiopathology Parkinson's disease Receptors, Dopamine D1 - antagonists & inhibitors Receptors, Dopamine D1 - physiology Receptors, Dopamine D2 - physiology Sulpiride - metabolism
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