Immunoglobulin-secreting cells in various maternal lymphoid tissues during syngeneic and allogeneic murine pregnancy
The effects of syngeneic (CBA×CBA) and allogeneic ( CBA× C57 B1 ) pregnancy on immunoglobulin (Ig)-secreting cells in various maternal organs/tissues have been investigated by using the protein A plaque assay. The following organs/tissues were examined: a ) spleen, b ) cervical nodes, c ) inguinal n...
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| Veröffentlicht in: | Developmental and comparative immunology 1984-01, Vol.8 (4), p.921-929 |
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| container_title | Developmental and comparative immunology |
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| creator | Mattsson, Ragnar Mattsson, Anita |
| description | The effects of syngeneic (CBA×CBA) and allogeneic (
CBA×
C57
B1
) pregnancy on immunoglobulin (Ig)-secreting cells in various maternal organs/tissues have been investigated by using the protein A plaque assay. The following organs/tissues were examined:
a
) spleen,
b
) cervical nodes,
c
) inguinal nodes,
d
) mesenteric nodes,
e
) paraaortic (uterus-draining) nodes,
f
) Peyer's patches, and
g
) bone marrow (femur). The changes observed were similar and of the same magnitude in all pregnant animals, irrespective of the type of mating. At mid-gestation (day 14) a distinct increase in Ig secretors was observed, predominantly in the spleen. At the end of pregnancy (day 20) the para-aortic nodes contained dramatically increased numbers of plaque forming cells. A slight increase in both IgM and IgG-secreting cells was also seen in bone marrow at the very end of pregnancy, while Peyer's patches and the nodes of neck and legs appeared to be unaffected throughout the period of gestation. |
| doi_str_mv | 10.1016/0145-305X(84)90074-0 |
| format | Article |
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CBA×
C57
B1
) pregnancy on immunoglobulin (Ig)-secreting cells in various maternal organs/tissues have been investigated by using the protein A plaque assay. The following organs/tissues were examined:
a
) spleen,
b
) cervical nodes,
c
) inguinal nodes,
d
) mesenteric nodes,
e
) paraaortic (uterus-draining) nodes,
f
) Peyer's patches, and
g
) bone marrow (femur). The changes observed were similar and of the same magnitude in all pregnant animals, irrespective of the type of mating. At mid-gestation (day 14) a distinct increase in Ig secretors was observed, predominantly in the spleen. At the end of pregnancy (day 20) the para-aortic nodes contained dramatically increased numbers of plaque forming cells. A slight increase in both IgM and IgG-secreting cells was also seen in bone marrow at the very end of pregnancy, while Peyer's patches and the nodes of neck and legs appeared to be unaffected throughout the period of gestation.</description><identifier>ISSN: 0145-305X</identifier><identifier>EISSN: 1879-0089</identifier><identifier>DOI: 10.1016/0145-305X(84)90074-0</identifier><identifier>PMID: 6542879</identifier><identifier>CODEN: DCIMDQ</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Animals ; Antibody-Producing Cells - immunology ; Applied sciences ; Exact sciences and technology ; Female ; Gestational Age ; Immunoglobulin G - biosynthesis ; Immunoglobulin M - biosynthesis ; Immunoglobulins - biosynthesis ; Lymphoid Tissue - anatomy & histology ; Lymphoid Tissue - immunology ; Mice ; Mice, Inbred Strains ; Organ Size ; Other techniques and industries ; Pregnancy ; Pregnancy, Animal ; Species Specificity</subject><ispartof>Developmental and comparative immunology, 1984-01, Vol.8 (4), p.921-929</ispartof><rights>1984</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c417t-6e4a95aec2ba94e87b1ed1dcf495578b2a97b66ead2cc15d2fbe17c167731c623</citedby><cites>FETCH-LOGICAL-c417t-6e4a95aec2ba94e87b1ed1dcf495578b2a97b66ead2cc15d2fbe17c167731c623</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0145305X84900740$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8834888$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6542879$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mattsson, Ragnar</creatorcontrib><creatorcontrib>Mattsson, Anita</creatorcontrib><title>Immunoglobulin-secreting cells in various maternal lymphoid tissues during syngeneic and allogeneic murine pregnancy</title><title>Developmental and comparative immunology</title><addtitle>Dev Comp Immunol</addtitle><description>The effects of syngeneic (CBA×CBA) and allogeneic (
CBA×
C57
B1
) pregnancy on immunoglobulin (Ig)-secreting cells in various maternal organs/tissues have been investigated by using the protein A plaque assay. The following organs/tissues were examined:
a
) spleen,
b
) cervical nodes,
c
) inguinal nodes,
d
) mesenteric nodes,
e
) paraaortic (uterus-draining) nodes,
f
) Peyer's patches, and
g
) bone marrow (femur). The changes observed were similar and of the same magnitude in all pregnant animals, irrespective of the type of mating. At mid-gestation (day 14) a distinct increase in Ig secretors was observed, predominantly in the spleen. At the end of pregnancy (day 20) the para-aortic nodes contained dramatically increased numbers of plaque forming cells. A slight increase in both IgM and IgG-secreting cells was also seen in bone marrow at the very end of pregnancy, while Peyer's patches and the nodes of neck and legs appeared to be unaffected throughout the period of gestation.</description><subject>Animals</subject><subject>Antibody-Producing Cells - immunology</subject><subject>Applied sciences</subject><subject>Exact sciences and technology</subject><subject>Female</subject><subject>Gestational Age</subject><subject>Immunoglobulin G - biosynthesis</subject><subject>Immunoglobulin M - biosynthesis</subject><subject>Immunoglobulins - biosynthesis</subject><subject>Lymphoid Tissue - anatomy & histology</subject><subject>Lymphoid Tissue - immunology</subject><subject>Mice</subject><subject>Mice, Inbred Strains</subject><subject>Organ Size</subject><subject>Other techniques and industries</subject><subject>Pregnancy</subject><subject>Pregnancy, Animal</subject><subject>Species Specificity</subject><issn>0145-305X</issn><issn>1879-0089</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUFr3DAQhUVoSTab_IMEdCglObiRbMmSL4EQkjQQ6KWB3IQsjbcqsryV7MD--8pZs8dWBwnxvnnMvEHogpJvlND6hlDGi4rwtyvJrhtCBCvIEVpRKZqCENl8QqsDcoJOU_pN8pGUHKPjmrMycys0Pvf9FIaNH9rJu1AkMBFGFzbYgPcJu4DfdXTDlHCvR4hBe-x3_fbX4CweXUoTJGynOFekXdhAAGewDhZr74fl28864G2ETdDB7M7Q5077BOfLu0avjw8_778XLz-enu_vXgrDqBiLGphuuAZTtrphIEVLwVJrOtZwLmRb6ka0dQ3alsZQbsuuBSoMrYWoqKnLao2-7n23cfiTGx1V79I8lw6QJ1KCy5oRRv4LUpbzrHiTQbYHTRxSitCpbXS9jjtFiZq3oubI1Ry5kkx9bEXN_peL_9T2YA9Fyxqy_mXRdTLadzGn5NIBk7JiMl9rdLvHIIf27iCqZBwEA9ZFMKOyg_t3H38BGmmsTw</recordid><startdate>19840101</startdate><enddate>19840101</enddate><creator>Mattsson, Ragnar</creator><creator>Mattsson, Anita</creator><general>Elsevier Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19840101</creationdate><title>Immunoglobulin-secreting cells in various maternal lymphoid tissues during syngeneic and allogeneic murine pregnancy</title><author>Mattsson, Ragnar ; Mattsson, Anita</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-6e4a95aec2ba94e87b1ed1dcf495578b2a97b66ead2cc15d2fbe17c167731c623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Animals</topic><topic>Antibody-Producing Cells - immunology</topic><topic>Applied sciences</topic><topic>Exact sciences and technology</topic><topic>Female</topic><topic>Gestational Age</topic><topic>Immunoglobulin G - biosynthesis</topic><topic>Immunoglobulin M - biosynthesis</topic><topic>Immunoglobulins - biosynthesis</topic><topic>Lymphoid Tissue - anatomy & histology</topic><topic>Lymphoid Tissue - immunology</topic><topic>Mice</topic><topic>Mice, Inbred Strains</topic><topic>Organ Size</topic><topic>Other techniques and industries</topic><topic>Pregnancy</topic><topic>Pregnancy, Animal</topic><topic>Species Specificity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mattsson, Ragnar</creatorcontrib><creatorcontrib>Mattsson, Anita</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Developmental and comparative immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mattsson, Ragnar</au><au>Mattsson, Anita</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Immunoglobulin-secreting cells in various maternal lymphoid tissues during syngeneic and allogeneic murine pregnancy</atitle><jtitle>Developmental and comparative immunology</jtitle><addtitle>Dev Comp Immunol</addtitle><date>1984-01-01</date><risdate>1984</risdate><volume>8</volume><issue>4</issue><spage>921</spage><epage>929</epage><pages>921-929</pages><issn>0145-305X</issn><eissn>1879-0089</eissn><coden>DCIMDQ</coden><abstract>The effects of syngeneic (CBA×CBA) and allogeneic (
CBA×
C57
B1
) pregnancy on immunoglobulin (Ig)-secreting cells in various maternal organs/tissues have been investigated by using the protein A plaque assay. The following organs/tissues were examined:
a
) spleen,
b
) cervical nodes,
c
) inguinal nodes,
d
) mesenteric nodes,
e
) paraaortic (uterus-draining) nodes,
f
) Peyer's patches, and
g
) bone marrow (femur). The changes observed were similar and of the same magnitude in all pregnant animals, irrespective of the type of mating. At mid-gestation (day 14) a distinct increase in Ig secretors was observed, predominantly in the spleen. At the end of pregnancy (day 20) the para-aortic nodes contained dramatically increased numbers of plaque forming cells. A slight increase in both IgM and IgG-secreting cells was also seen in bone marrow at the very end of pregnancy, while Peyer's patches and the nodes of neck and legs appeared to be unaffected throughout the period of gestation.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>6542879</pmid><doi>10.1016/0145-305X(84)90074-0</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0145-305X |
| ispartof | Developmental and comparative immunology, 1984-01, Vol.8 (4), p.921-929 |
| issn | 0145-305X 1879-0089 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75864040 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Antibody-Producing Cells - immunology Applied sciences Exact sciences and technology Female Gestational Age Immunoglobulin G - biosynthesis Immunoglobulin M - biosynthesis Immunoglobulins - biosynthesis Lymphoid Tissue - anatomy & histology Lymphoid Tissue - immunology Mice Mice, Inbred Strains Organ Size Other techniques and industries Pregnancy Pregnancy, Animal Species Specificity |
| title | Immunoglobulin-secreting cells in various maternal lymphoid tissues during syngeneic and allogeneic murine pregnancy |
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