A peptide from ICAM-2 binds to the leukocyte integrin CD11a/CD18 and inhibits endothelial cell adhesion

Numerous leukocyte functions depend on adhesive intercellular interactions. The leukocyte-specific integrins CD11a/CD18 (lymphocyte function-associated antigen-1 (LFA-1)) and CD11b/CD18 (complement type 3 receptor (Mac-1)), which bind to the intercellular adhesion molecules ICAM-1 and ICAM-2, play a...

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Veröffentlicht in:	The Journal of biological chemistry 1993-08, Vol.268 (23), p.17513-17518
Hauptverfasser:	RUI LI, NORTAMO, P, VALMU, L, TOLVANEN, M, HUUSKONEN, J, KANTOR, C, GAHMBERG, C. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical, structural and metabolic biochemistry Animals Antigens, CD Binding and carrier proteins Biological and medical sciences Cell Adhesion Cell Adhesion Molecules - metabolism Electrophoresis, Polyacrylamide Gel Endothelium, Vascular - cytology Endothelium, Vascular - metabolism Fundamental and applied biological sciences. Psychology Humans Hybrid Cells Lymphocyte Function-Associated Antigen-1 - metabolism Mice Models, Molecular Molecular Sequence Data Peptide Fragments - metabolism Proteins Sequence Homology, Amino Acid
Online-Zugang:	Volltext
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