Identification of a Chymotrypsin‐Like Mast Cell Protease in Rat Brain Capable of Generating the N‐Terminus of the Alzheimer Amyloid β‐Protein

: Cleavage after Met596 of the β‐amyloid precursor protein to generate the N‐terminus of β‐protein indicates the activity of a protease having chymotrypsin‐like specificity. A chymotrypsin‐like protease is further implicated in Alzheimer's disease by the increased synthesis of the protease inhi...

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